3-Aminoisobutanoic acid
3-Aminoisobutanoic acid structure
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Common Name | 3-Aminoisobutanoic acid | ||
|---|---|---|---|---|
| CAS Number | 144-90-1 | Molecular Weight | 103.120 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 223.6±23.0 °C at 760 mmHg | |
| Molecular Formula | C4H9NO2 | Melting Point | 246.72°C (estimate) | |
| MSDS | USA | Flash Point | 89.0±22.6 °C | |
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Automated screening of urine samples for carbohydrates, organic and amino acids after treatment with urease.
J. Chromatogr. A. 562(1-2) , 125-38, (1991) Eighty-five clinical urine samples and nineteen urine samples previously found by other laboratories to suggest genetic metabolic defects were prepared for trimethylsilylation by treatment with urease, followed by azeotropic dehydration. The "Target Analyte S... |
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Urinary and plasma organic acids and amino acids in chronic fatigue syndrome.
Clin. Chim. Acta 361(1-2) , 150-8, (2005) Previous work by others have suggested the occurrence of one or more chemical or metabolic 'markers' for ME/CFS including specific amino acids and organic acids and a number of unidentified compounds (CFSUM1, CFSUM2). We have shown elsewhere that CFSUM1 is pa... |
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Differential 12C-/13C-isotope dansylation labeling and fast liquid chromatography/mass spectrometry for absolute and relative quantification of the metabolome.
Anal. Chem. 81(10) , 3919-32, (2009) We report a new quantitative metabolome profiling technique based on differential (12)C-/(13)C-isotope dansylation labeling of metabolites, fast liquid chromatography (LC) separation and electrospray ionization Fourier-transform ion cyclotron resonance mass s... |
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New insights in dihydropyrimidine dehydrogenase deficiency: a pivotal role for beta-aminoisobutyric acid?
Biochem. J. 379(Pt 1) , 119-24, (2004) DPD (dihydropyrimidine dehydrogenase) constitutes the first step of the pyrimidine degradation pathway, in which the pyrimidine bases uracil and thymine are catabolized to beta-alanine and the R-enantiomer of beta-AIB (beta-aminoisobutyric acid) respectively.... |
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[Beta-alanine aminotransferases on pyrimidine catabolism].
Seikagaku. 73(9) , 1151-4, (2001)
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Dual-column cation-exchange chromatographic method for beta-aminoisobutyric acid and beta-alanine in biological samples.
Clin. Chem. 24(8) , 1373-80, (1978) A rapid, automated chromatographic method has been developed for the quantitation of the nucleic acid catabolites beta-aminoisobutyric acid and beta-alanine in urine, serum, and other physiological fluids. The analyses were performed on a modified Beckman 121... |
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beta-Ureidopropionase deficiency: an inborn error of pyrimidine degradation associated with neurological abnormalities.
Hum. Mol. Genet. 13(22) , 2793-801, (2004) beta-Ureidopropionase deficiency is an inborn error of the pyrimidine degradation pathway, affecting the cleavage of N-carbamyl-beta-alanine and N-carbamyl-beta-aminoisobutyric acid. In this study, we report the elucidation of the genetic basis underlying a b... |
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Role of cyclooxygenases 1 and 2 in the modulation of neuromuscular functions in the distal colon of humans and mice.
Gut 54(5) , 608-16, (2005) Cyclooxygenase isoforms (COX-1, COX-2) may exert differential regulatory actions on enteric motor functions under normal or pathological conditions.To examine the occurrence and functions of COX-1 and COX-2 in the neuromuscular compartment of normal distal co... |
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Radioimmunoassay for atropine and l-hyoscyamine.
Acta Pharmacol. Toxicol. (Copenh.) 47(3) , 208-12, (1980) A simple, specific and sensitive radioimmunoassay is described for atropine (dl-hyoscyamine) and l-hyoscyamine. Antiserum was obtained from rabbits immunized with an immunogen prepared by coupling l-hyoscyamine to human serum albumin. By using 3H-atropine as ... |
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Detection of beta-ureidopropionase deficiency with HPLC-electrospray tandem mass spectrometry and confirmation of the defect at the enzyme level.
J. Inherit. Metab. Dis. 24(7) , 725-32, (2001) The pyrimidine bases uracil and thymine are degraded via the consecutive action of three enzymes to beta-alanine and beta-aminoisobutyric acid, respectively. To date, a number of patients have been described with a deficiency of dihydropyrimidine dehydrogenas... |