![]() Promethazine hcl structure
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Common Name | Promethazine hcl | ||
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CAS Number | 132539-07-2 | Molecular Weight | 412.90800 | |
Density | N/A | Boiling Point | 487.8ºC at 760mmHg | |
Molecular Formula | C20H29ClN2O5 | Melting Point | 195-197ºC | |
MSDS | Chinese USA | Flash Point | 248.8ºC |
Remifentanil has a minimal direct effect on sinoatrial node pacemaker activity in the Guinea pig heart.
Anesth. Analg. 117(5) , 1072-7, (2013) Whereas remifentanil administration is associated with severe bradycardia, it has yet to be fully investigated whether the negative chronotropic action of remifentanil is mediated by its direct action on sinoatrial (SA) node pacemaker activity in the heart ve... |
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The antiapoptotic effect of remifentanil on the immature mouse brain: an ex vivo study.
Anesth. Analg. 118(5) , 1041-51, (2014) The use of remifentanil in a context of potential prematurity led us to explore ex vivo the opioid effects on the immature mouse brain. Remifentanil enhances medullary glutamatergic N-methyl-D-aspartate (NMDA) receptor activity. Furthermore, in neonatal mouse... |
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The biological effects of hsa-miR-1908 in human adipocytes.
Mol. Biol. Rep. 42(5) , 927-35, (2015) MicroRNAs (miRNAs) are small non-coding RNAs involved in the regulation of gene expression. MiR-1908 is a recently identified miRNA that is highly expressed in human adipocytes. However, it is not known what role of miR-1908 is involved in the regulation of h... |
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Nicardipine infusion for hypotensive anesthesia during orthognathic surgery has protective effect on renal function.
J. Oral Maxillofac. Surg. 72(1) , 41-6, (2014) Hypotensive anesthesia may adversely affect renal function. The purpose of this study was to evaluate the renoprotective effect of nicardipine in patients undergoing orthognathic surgery under hypotensive anesthesia.In this double-blinded randomized controlle... |
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Accuracy of the composite variability index as a measure of the balance between nociception and antinociception during anesthesia.
Anesth. Analg. 119(2) , 288-301, (2014) The Composite Variability Index (CVI), derived from the electroencephalogram, was developed to assess the antinociception-nociception balance, whereas the Bispectral Index (BIS) was developed to assess the hypnotic state during anesthesia. We studied the rela... |
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Analysis of transthoracic echocardiographic data in major vascular surgery from a prospective randomised trial comparing sevoflurane and fentanyl with propofol and remifentanil anaesthesia.
Anaesthesia 69(6) , 558-72, (2014) The aim of this study was to define pre-operative echocardiographic data and explore if postoperative indices of cardiac function after open abdominal aortic surgery were affected by the anaesthetic regimen. We hypothesised that volatile anaesthesia would imp... |
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Performance of propofol target-controlled infusion models in the obese: pharmacokinetic and pharmacodynamic analysis.
Anesth. Analg. 119(2) , 302-10, (2014) Obesity is associated with important physiologic changes that can potentially affect the pharmacokinetic (PK) and pharmacodynamic (PD) profile of anesthetic drugs. We designed this study to assess the predictive performance of 5 currently available propofol P... |
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Dexmedetomidine reduces propofol and remifentanil requirements during bispectral index-guided closed-loop anesthesia: a double-blind, placebo-controlled trial.
Anesth. Analg. 118(5) , 946-55, (2014) The α2-adrenergic agonist dexmedetomidine is a sedative and can be used as an adjunct to anesthetics. Our primary goal was thus to determine the extent to which dexmedetomidine reduces the requirement for propofol and remifentanil.This double-blinded, randomi... |
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Limb remote ischemic preconditioning attenuates lung injury after pulmonary resection under propofol-remifentanil anesthesia: a randomized controlled study.
Anesthesiology 121(2) , 249-59, (2014) Remote ischemic preconditioning (RIPC) may confer the protection in critical organs. The authors hypothesized that limb RIPC would reduce lung injury in patients undergoing pulmonary resection.In a randomized, prospective, parallel, controlled trial, 216 pati... |
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Intubation without muscle relaxation for suspension laryngoscopy: a randomized, controlled study.
Niger. J. Clin. Pract. 17(4) , 456-61, (2014) The objective of the following study is to examine the effectiveness and safety of suspension laryngoscopy under intubation with propofol and remifentanil alone for vocal fold nodule (VFN) excision.A total of 40 patients were equally and randomly assigned to ... |