2-Cyanoethyl diisopropylamidochlorophosphite

2-Cyanoethyl diisopropylamidochlorophosphite Structure
2-Cyanoethyl diisopropylamidochlorophosphite structure
Common Name 2-Cyanoethyl diisopropylamidochlorophosphite
CAS Number 89992-70-1 Molecular Weight 236.679
Density 1.061 g/mL at 25 °C(lit.) Boiling Point 343.8±0.0 °C at 760 mmHg
Molecular Formula C9H18ClN2OP Melting Point N/A
MSDS USA Flash Point 135.8±28.4 °C
Symbol GHS02 GHS05
GHS02, GHS05
Signal Word Danger

Synthesis of non-natural sequence-encoded polymers using phosphoramidite chemistry.

J. Am. Chem. Soc. 137 , 5629-35, (2015)

Sequence-defined non-natural polyphosphates were prepared using iterative phosphoramidite protocols on a polystyrene solid support. Three monomers were used in this work: 2-cyanoethyl (3-dimethoxytrityloxy-propyl) diisopropylphosphoramidite (0), 2-cyanoethyl ...

Proteomic-based approach to gain insight into reprogramming of THP-1 cells exposed to Leishmania donovani over an early temporal window.

Bioconjug. Chem. 4 , 499, (1993)

Leishmania donovani, a protozoan parasite, is the causative agent of visceral leishmaniasis. It lives and multiplies within the harsh environment of macrophages. In order to investigate how intracellular parasite manipulate the host cell environment, we under...

Solid-phase reagents for selective monophosphorylation of carbohydrates and nucleosides.

J. Org. Chem. 70(3) , 1100-3, (2005)

Two classes of aminomethyl polystyrene resin-bound linkers of p-acetoxybenzyl alcohol were subjected to reactions with 2-cyanoethyl N,N-diisopropylchlorophosphoramidite to produce the corresponding polymer-bound phosphitylating reagents. These were reacted wi...

Synthesis of uridine phosphoramidite analogs: reagents for site-specific incorporation of photoreactive sites into RNA sequences.

Bioconjug. Chem. 5(6) , 508-12, (1994)

The synthesis of three new photoactive RNA phosphoramidites, 5-bromouridine, 5-iodouridine, and O4-triazolouridine, is reported. The 5' OH of bromouridine and iodouridine were protected as dimethoxytrityl ether using dimethoxytrityl chloride and pyridine. Sel...

Tetrahedron Lett. 35 , 5221, (1994)

Tetrahedron Lett. 34 , 6189, 6721, (1993)

Tetrahedron Lett. 45 , 509, (2004)

Org. Process Res. Dev. 10 , 1238, (2006)