(Trifluoromethyl)trimethylsilane

(Trifluoromethyl)trimethylsilane Structure
(Trifluoromethyl)trimethylsilane structure
Common Name (Trifluoromethyl)trimethylsilane
CAS Number 81290-20-2 Molecular Weight 142.19
Density 1.0±0.1 g/cm3 Boiling Point 49.3±40.0 °C at 760 mmHg
Molecular Formula C4H9F3Si Melting Point N/A
MSDS Chinese USA Flash Point -16.4±27.3 °C
Symbol GHS02
GHS02
Signal Word Danger

Facile synthesis of TMS-protected trifluoromethylated alcohols using trifluoromethyltrimethylsilane (TMSCF3) and various nucleophilic catalysts in DMF.

J. Org. Chem. 71 , 6806, (2006)

Organofluorine compounds are becoming increasingly important in different fields, such as material science, agro chemistry, and the pharmaceutical industry. Nucleophilic trifluoromethylation is one of the widely used methods to incorporate a trifluoromethyl m...