4,4'-Methylenediphenol

4,4'-Methylenediphenol Structure
4,4'-Methylenediphenol structure
Common Name 4,4'-Methylenediphenol
CAS Number 620-92-8 Molecular Weight 200.233
Density 1.2±0.1 g/cm3 Boiling Point 390.0±22.0 °C at 760 mmHg
Molecular Formula C13H12O2 Melting Point 162-164 °C
MSDS Chinese USA Flash Point 192.9±16.9 °C
Symbol GHS07
GHS07
Signal Word Warning

Determination of bisphenols in beverages by mixed-mode solid-phase extraction and liquid chromatography coupled to tandem mass spectrometry.

J. Chromatogr. A. 1422 , 230-8, (2015)

Facing growing restrictions on the use of bisphenol A in food contact materials, several bisphenol analogs are arising as major alternatives to replace this chemical in most of its applications. This work reports a simple and robust method based on mixed-mode...

A simple method for the enrichment of bisphenols using boron nitride.

Food Chem. 194 , 149-55, (2015)

A simple solid-phase extraction method for the enrichment of 5 bisphenol derivatives using hexagonal boron nitride (BN) was developed. BN was applied to concentrate bisphenol derivatives in spiked water samples and the compounds were analyzed using HPLC coupl...

Screening of bisphenol A, triclosan and paraben analogues as modulators of the glucocorticoid and androgen receptor activities.

Toxicol. In Vitro 29(1) , 8-15, (2014)

A homeostasis of the glucocorticoid and androgen endocrine system is essential to human health. Their disturbance can lead to various diseases, for example cardiovascular, inflammatory and autoimmune diseases, infertility, cancer. Fifteen widely used industri...

Structural bisphenol analogues differentially target steroidogenesis in murine MA-10 Leydig cells as well as the glucocorticoid receptor.

Toxicology 329 , 10-20, (2015)

Although much information on the endocrine activity of bisphenol A (BPA) is available, a proper human hazard assessment of analogues that are believed to have a less harmful toxicity profile is lacking. Here the possible effects of BPA, bisphenol F (BPF), bis...

A chemical screening approach reveals that indole fluorescence is quenched by pre-fibrillar but not fibrillar amyloid-beta.

Bioorg. Med. Chem. Lett. 19 , 4952-7, (2009)

Aggregated amyloid-beta (Abeta) peptide is implicated in the pathology of Alzheimer's disease. In vitro and in vivo, these aggregates are found in a variety of morphologies, including globular oligomers and linear fibrils, which possess distinct biological ac...

A simple approach for ultrasensitive detection of bisphenols by multiplexed surface-enhanced Raman scattering.

Anal. Chim. Acta 888 , 118-25, (2015)

Bisphenol A (BPA) is well known for its use in plastic manufacture and thermal paper production despite its risk of health toxicity as an endocrine disruptor in humans. Since the publication of new legislation regarding the use of BPA, manufacturers have begu...

Studies on the interactions of bisphenols with anionic phospholipids of decomposer membranes in model systems.

Biochim. Biophys. Acta 1858 , 756-66, (2016)

Bisphenol A (BPA) and other bisphenols constitute a class of organic pollutants, which because of their estrogenic properties, low dose activity and bioaccumulation pose considerable risk for public health as well as for the environment. Accumulated in the se...

Effects of bisphenol analogues on steroidogenic gene expression and hormone synthesis in H295R cells.

Chemosphere 147 , 19-Sep, (2016)

The use of Bisphenol A (BPA) has been regulated in many countries because of its potential adverse effects on human health. As a result of the restriction, structural anologues such as bisphenol S (BPS) and bisphenol F (BPF) have already been used for industr...

Novel Finding of Widespread Occurrence and Accumulation of Bisphenol A Diglycidyl Ethers (BADGEs) and Novolac Glycidyl Ethers (NOGEs) in Marine Mammals from the United States Coastal Waters.

Environ. Sci. Technol. 50 , 1703-10, (2016)

Bisphenol A diglycidyl ether (BADGE)- and bisphenol F diglycidyl ether (BFDGE)-based epoxy resins have a broad range of applications, including serving as inner coatings of food and beverage cans and as protective coatings in marine construction. Prior to thi...