2-(Fluorosulfonyl)difluoroacetic acid
2-(Fluorosulfonyl)difluoroacetic acid structure
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Common Name | 2-(Fluorosulfonyl)difluoroacetic acid | ||
|---|---|---|---|---|
| CAS Number | 1717-59-5 | Molecular Weight | 178.087 | |
| Density | 1.9±0.1 g/cm3 | Boiling Point | 197.8±40.0 °C at 760 mmHg | |
| Molecular Formula | C2HF3O4S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 73.4±27.3 °C | |
| Symbol |
GHS05, GHS06 |
Signal Word | Danger | |
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Facile one-pot synthesis of N-difluoromethyl-2-pyridone derivatives.
Org. Lett. 8(17) , 3805-8, (2006) [reaction: see text] A novel one-pot synthesis of N-difluoromethyl-2-pyridones is described. N-(Pyridin-2-yl)acetamide derivatives were excellent precursors for the preparation of N-difluoromethyl-2-pyridone derivatives. Difluoromethylation of 2-acetaminopyri... |
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Synthesis and biological evaluation of N-difluoromethyl-1,2-dihydropyrid-2-one acetic acid regioisomers: dual inhibitors of cyclooxygenases and 5-lipoxygenase.
Bioorg. Med. Chem. Lett. 20 , 2168-73, (2010) A new group of acetic acid (7a-c, R(1) = H), and propionic acid (7d-f, R(1) = Me), regioisomers wherein a N-difluoromethyl-1,2-dihydropyrid-2-one moiety is attached via its C-3, C-4, and C-5 position was synthesized. This group of compounds exhibited a more p... |
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Preparation and use of a new difluorocarbene reagent Dolbier, W. R., Jr.; et al.
Organic Synth. 80 , 172-176, (2003)
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Trimethylsilyl fluorosulfonyldifluoroacetate (TFDA): a new, highly efficient difluorocarbene reagent Dolbier, William R.; et al.
J. Fluor. Chem. 3rd ed., 125 , 459-469, (2004)
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Free radical fluoroalkylation of terminal alkenes and alkynes with iododifluoromethanesulfonamides Zhu, J. M.; et al.
Sci. China Chem. 1st ed., 54 , 95-102, (2011)
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Free radical fluoroalkylation of terminal alkenes and alkynes with iododifluoromethanesulfonamides. Zhu JM, et al.
Sci. China Chem. 54(1) , 95-102, (2011)
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