Hexanoic acid, 6-(acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3, 3a-dihydroxy-3,6, 9-trimethyl-8-[(2-methyl-1-oxo-2-butenyl)oxy]-2-oxo-4-(1-oxobutoxy )azuleno[4,5-b]furan-7-yl ester, [3R-[3.alpha.,3a.
![Hexanoic acid, 6-(acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3, 3a-dihydroxy-3,6, 9-trimethyl-8-[(2-methyl-1-oxo-2-butenyl)oxy]-2-oxo-4-(1-oxobutoxy )azuleno[4,5-b]furan-7-yl ester, [3R-[3.alpha.,3a. Structure](https://image.chemsrc.com/caspic/106/67526-94-7.png)
Hexanoic acid, 6-(acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3, 3a-dihydroxy-3,6, 9-trimethyl-8-[(2-methyl-1-oxo-2-butenyl)oxy]-2-oxo-4-(1-oxobutoxy )azuleno[4,5-b]furan-7-yl ester, [3R-[3.alpha.,3a. structure
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Common Name | Hexanoic acid, 6-(acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3, 3a-dihydroxy-3,6, 9-trimethyl-8-[(2-methyl-1-oxo-2-butenyl)oxy]-2-oxo-4-(1-oxobutoxy )azuleno[4,5-b]furan-7-yl ester, [3R-[3.alpha.,3a. | ||
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| CAS Number | 67526-94-7 | Molecular Weight | 622.70 | |
| Density | 1.26g/cm3 | Boiling Point | 673.3ºC at 760 mmHg | |
| Molecular Formula | C32H46O12 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 203.8ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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ER stress induces epithelial differentiation in the mouse oesophagus.
Gut 64(2) , 195-202, (2015) Stress in the endoplasmic reticulum (ER) leads to activation of the unfolded protein response (UPR). Xbp1, a key component of the UPR has recently been linked to the risk of developing oesophageal squamous cell carcinoma, suggesting an important role for the ... |
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Fulfenamic acid sensitive, Ca(2+)-dependent inward current induced by nicotinic acetylcholine receptors in dopamine neurons.
Neurosci. Res. 46(4) , 463-73, (2003) Nicotinic acetylcholine receptors (nAChRs) exhibit high Ca(2+) permeabilities and the Ca(2+)-influx through the nAChRs may be involved in regulation of a variety of signal processing in the postsynaptic neurons. The mesencephalic dopamine (DA) neurons receive... |
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Cellular calcium deficiency plays a role in neuronal death caused by proteasome inhibitors.
J. Neurochem. 109(5) , 1225-36, (2009) Cytosolic Ca(2+) concentration ([Ca(2+)](i)) is reduced in cultured neurons undergoing neuronal death caused by inhibitors of the ubiquitin proteasome system. Activation of calcium entry via voltage-gated Ca(2+) channels restores cytosolic Ca(2+) levels and r... |
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Glycopeptide export from mammalian microsomes is independent of calcium and is distinct from oligosaccharide export.
Glycobiology 10(4) , 383-91, (2000) Glycopeptides are exported from the endoplasmic reticulum to the cytosol of eukaryotic membranes in an ATP- and cytosol-requiring process (Romisch and Ali, 1997, Proc. Natl. Acad. Sci. USA,94, 6730-6734). Oligosaccharides of the polymannose-type are also expo... |
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Amyloid-β peptide-induced secretion of endoplasmic reticulum chaperone glycoprotein GRP94.
J. Alzheimers Dis. 27(1) , 61-73, (2011) Amyloid-β (Aβ) peptide-induced neurotoxicity is typically associated with cell death through mechanisms not entirely understood. Here, we investigated stress signaling events triggered by soluble Aβ in differentiated rat neuronal-like PC12 cells. Morphologic ... |
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GIF-0173 protects against cerebral infarction through DP1 receptor activation.
Exp. Neurol. 219(2) , 481-91, (2009) The neuroprotective effects and mechanism of action of GIF-0173, a Delta12-prostaglandin J analogue, were investigated in the early phase of cerebral ischemia. GIF-0173 was administered intravenously immediately following middle cerebral artery occlusion (MCA... |
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Calcium entry is regulated by Zn2+ in relation to extracellular ionic environment in human airway epithelial cells.
Respir. Physiol. Neurobiol. 170(1) , 67-75, (2010) The extracellular pH, sodium and divalent cation concentrations influence the ATP-induced changes in cytosolic Ca(2+) concentration ([Ca(2+)](i)). This elevation of [Ca(2+)](i) and activation of Ca(2+)-dependent Cl(-) channels represent a possible therapeutic... |
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Distinct intracellular Ca2+ response to extracellular adenosine triphosphate in pancreatic beta-cells in rats and mice.
Endocrine 22(3) , 185-92, (2003) Extracellular adenosine triphosphate (ATP) has distinct effects on insulin secretion from pancreatic beta-cells between rats and mice. Using a confocal microscope, we compared changes between rats and mice in cytosolic free calcium concentration ([Ca2+]c) in ... |
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Improved expression and characterization of Ca2+-ATPase and phospholamban in High-Five cells.
Protein Expr. Purif. 34(1) , 56-67, (2004) The Ca2+-ATPase accounts for the majority of Ca2+ removed from the cytoplasm during cardiac muscle relaxation. The Ca2+-ATPase is regulated by phospholamban, a 52 amino acid phosphoprotein, which inhibits Ca2+-ATPase activity by decreasing the apparent affini... |
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Sildenafil decreases rat tracheal hyperresponsiveness to carbachol and changes canonical transient receptor potential gene expression after antigen challenge.
Braz. J. Med. Biol. Res. 44(6) , 562-72, (2011) Inhibition of type-5 phosphodiesterase by sildenafil decreases capacitative Ca2+ entry mediated by transient receptor potential proteins (TRPs) in the pulmonary artery. These families of channels, especially the canonical TRP (TRPC) subfamily, may be involved... |