Glutaryl coenzyme A lithium

Glutaryl coenzyme A lithium Structure
Glutaryl coenzyme A lithium structure
Common Name Glutaryl coenzyme A lithium
CAS Number 103192-48-9 Molecular Weight 887.56700
Density 1.88g/cm3 Boiling Point N/A
Molecular Formula C26H41LiN7O19P3S Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

Cerebral haemodynamics in patients with glutaryl-coenzyme A dehydrogenase deficiency.

Brain 133 , 76-92, (2010)

In glutaric aciduria type 1, glutaryl-coenzyme A and its derivatives are produced from intracerebral lysine and entrapped at high concentrations within the brain, where they interfere with energy metabolism. Biochemical toxicity is thought to trigger stroke-l...

Conversion of a decarboxylating to a non-decarboxylating glutaryl-coenzyme A dehydrogenase by site-directed mutagenesis.

FEBS Lett. 585 , 1317-1321, (2011)

Glutaryl-coenzyme A (CoA) dehydrogenases (GDHs) are acyl-CoA dehydrogenases, which usually dehydrogenate and decarboxylate the substrate to crotonyl-CoA. In some anaerobic bacteria, non-decarboxylating GDHs exist that release glutaconyl-CoA (2,3-dehydroglutar...

Structural basis for promoting and preventing decarboxylation in glutaryl-coenzyme a dehydrogenases.

Biochemistry 49 , 5350-5357, (2010)

Glutaryl-coenzyme A dehydrogenases (GDHs) involved in amino acid degradation were thought to catalyze both the dehydrogenation and decarboxylation of glutaryl-coenzyme A to crotonyl-coenzyme A and CO(2). Recently, a structurally related but nondecarboxylating...