AMG 9810

AMG 9810 Structure
AMG 9810 structure
Common Name AMG 9810
CAS Number 545395-94-6 Molecular Weight 337.412
Density 1.2±0.1 g/cm3 Boiling Point 512.5±50.0 °C at 760 mmHg
Molecular Formula C21H23NO3 Melting Point N/A
MSDS Chinese USA Flash Point 263.8±30.1 °C
Symbol GHS07
GHS07
Signal Word Warning

Spinal NKCC1 blockade inhibits TRPV1-dependent referred allodynia.

Mol. Pain 3 , 17, (2007)

The Na+, K+, 2Cl- type I cotransporter (NKCC1) and TRPV1 receptors, at the level of the dorsal horn, have been implicated in mediating allodynia in response to an inflammatory insult. The NKCC1 cotransporter regulates intracellular [Cl-] and thus the magnitud...

Endocannabinoid System and TRPV1 Receptors in the Dorsal Hippocampus of the Rats Modulate Anxiety-like Behaviors.

Iran. J. Basic Med. Sci. 15 , 795-802, (2013)

Fatty acid is amide hydrolase which reduce endogenous anandamide. Transient receptor potential vanilloid-1 (TRPV1) channels have been reported to have a role in the modulation of anxiety-like behaviors in rodents. In the present study, the effects of either e...