Gly-Gly-Gly-Gly-Gly-OH

Gly-Gly-Gly-Gly-Gly-OH Structure
Gly-Gly-Gly-Gly-Gly-OH structure
Common Name Gly-Gly-Gly-Gly-Gly-OH
CAS Number 7093-67-6 Molecular Weight 303.27200
Density 1.406g/cm3 Boiling Point 942.3ºC at 760 mmHg
Molecular Formula C10H17N5O6 Melting Point N/A
MSDS Chinese USA Flash Point 523.7ºC

Peptidoglycan crosslinking relaxation plays an important role in Staphylococcus aureus WalKR-dependent cell viability.

PLoS ONE 6 , e17054, (2011)

The WalKR two-component system is essential for viability of Staphylococcus aureus, a major pathogen. We have shown that WalKR acts as the master controller of peptidoglycan metabolism, yet none of the identified regulon genes explain its requirement for cell...

Modeling the electrophoresis of oligoglycines.

J. Sep. Sci. 33 , 2430-2438, (2010)

The electrophoretic mobility of low molecular mass oligoglycines is examined in this study using a "coarse-grained" bead modeling methodology [Pei, H., Allison, S. A., J. Chromatogr. A 2009, 1216, 1908-1916]. The advantage of focusing on these peptides is tha...

Site-specific tetrameric streptavidin-protein conjugation using sortase A.

J. Biotechnol. 152 , 37-42, (2011)

Streptavidin is tetrameric protein which has tight and specific biotin binding affinity, and streptavidin modification of proteins or small molecules is widely used for biotechnology tool. Here, we demonstrate site-specific streptavidin-protein conjugation us...

[Mode of action of microbial anti-MRSA agents].

Yakugaku Zasshi 132 , 37-44, (2012)

Methicillin-resistant Staphylococcus aureus (MRSA) is known as a major nosocomial pathogen that has also developed resistance to many antibiotics. Moreover, MRSA resistance to a last-resort antibiotic, vancomycin, has been reported. Therefore, new anti-infect...

Carnosine retards tumor growth in vivo in an NIH3T3-HER2/neu mouse model.

Mol. Cancer 9 , 2, (2010)

It was previously demonstrated that the dipeptide carnosine inhibits growth of cultured cells isolated from patients with malignant glioma. In the present work we investigated whether carnosine also affects tumor growth in vivo and may therefore be considered...

The Staphylococcus aureus peptidoglycan protects mice against the pathogen and eradicates experimentally induced infection.

PLoS ONE 6 , e28377, (2011)

Staphylococcus aureus, in spite of antibiotics, is still a major human pathogen causing a wide range of infections. The present study describes the new vaccine A170PG, a peptidoglycan-based vaccine. In a mouse model of infection, A170PG protects mice against ...