2-(Trifluoromethyl)phenylacetic acid

2-(Trifluoromethyl)phenylacetic acid Structure
2-(Trifluoromethyl)phenylacetic acid structure
Common Name 2-(Trifluoromethyl)phenylacetic acid
CAS Number 3038-48-0 Molecular Weight 204.146
Density 1.4±0.1 g/cm3 Boiling Point 249.9±35.0 °C at 760 mmHg
Molecular Formula C9H7F3O2 Melting Point 107-110 °C(lit.)
MSDS Chinese USA Flash Point 105.0±25.9 °C
Symbol GHS07
GHS07
Signal Word Warning

Cyclic RGD peptide analogues as antiplatelet antithrombotics.

J. Med. Chem. 35 , 2040, (1992)

Stimulation of platelets activates GPIIbIIIa, the heterodimeric integrin receptor, to bind fibrinogen (Fg), which results in platelet aggregation. GPIIbIIIa/Fg binding inhibitors are potentially suitable for acute use during and after thrombolytic therapy as ...

Effect of structure on potency and selectivity in 2,6-disubstituted 4-(2-arylethenyl)phenol lipoxygenase inhibitors.

J. Med. Chem. 33 , 1892, (1990)

A series of 2,6-disubstituted 4-(2-arylethenyl)phenols with potent human neutrophil 5-lipoxygenase (5-LO) inhibiting activity (IC50S in the 10(-7) M range) and weaker human platelet cyclooxygenase (CO) inhibiting activity (IC50S in the 10(-6) M range) is desc...