ferulic acid

ferulic acid Structure
ferulic acid structure
Common Name ferulic acid
CAS Number 1135-24-6 Molecular Weight 194.184
Density 1.3±0.1 g/cm3 Boiling Point 372.3±27.0 °C at 760 mmHg
Molecular Formula C10H10O4 Melting Point 168-172 °C(lit.)
MSDS Chinese USA Flash Point 150.5±17.2 °C
Symbol GHS07
GHS07
Signal Word Warning

Characterization of p-hydroxycinnamate catabolism in a soil Actinobacterium.

J. Bacteriol. 196(24) , 4293-303, (2014)

p-Hydroxycinnamates, such as ferulate and p-coumarate, are components of plant cell walls and have a number of commercial applications. Rhodococcus jostii RHA1 (RHA1) catabolizes ferulate via vanillate and the β-ketoadipate pathway. Here, we used transcriptom...

[Simultaneous determination of five organic acids in Kudiezi injection by HPLC].

Zhongguo Zhong Yao Za Zhi 38(19) , 3287-90, (2013)

The aim was to develop a high performance liquid chromatography method for simultaneous determination of five organic acids in Kudiezi injection. The Diamonsil C18 column (4.6 mm x 200 mm, 5 microm) was adopted with acetonitrile and water as the mobile phase ...

Spectroscopic studies on the in vitro antioxidant capacity of isopentyl ferulate.

Chem. Biol. Interact. 225 , 47-53, (2015)

Essential oils have played a prominent role in research on natural products, due to the high level of bioactive constituents, which include those derived from phenylpropanoids or terpenoids. This study aimed to evaluate the antioxidant capacity of isopentyl f...

Evaluation of a topical gel containing a novel combination of essential oils and antioxidants for reducing oral malodor in dogs.

Am. J. Vet. Res. 75(7) , 653-7, (2014)

To evaluate the effectiveness of a topically applied gel containing essential oils (menthol and thymol) and polyphenolic antioxidants (phloretin and ferulic acid) for reducing halitosis in dogs.20 dogs.A blinded crossover clinical trial was conducted. Dogs re...

[Analgesic effect of ferulic acid on CCI mice: behavior and neurobiological analysis].

Zhongguo Zhong Yao Za Zhi 38(21) , 3736-41, (2013)

To study the analgesic effect of chronic administration with ferulic acid, and preliminarily discuss its mechanism. Thermal hyperalgesia and mechanical allodynia tests were conducted to observe the analgesic effect of chronic administration with ferulic acid ...

[Optimization of supercritical fluid extraction of bioactive components in Ligusticum chuanxiong by orthogonal array design].

Zhongguo Zhong Yao Za Zhi 38(20) , 3484-8, (2013)

With the yields of ferulic acid, coniferylferulate, Z-ligustilide, senkyunolide A, butylidenephthalide, butylphthalide, senkyunolide I, senkyunolide H, riligustilide, levistolide A, and total pharmacologically active ingredient as evaluation indexes, the extr...

Ferulic acid attenuates focal cerebral ischemia-induced decreases in p70S6 kinase and S6 phosphorylation.

Neurosci. Lett. 555 , 7-11, (2013)

Ferulic acid exhibits neuroprotective effects against focal cerebral ischemia. PI3/K and Akt signaling pathways play an essential role in protecting against cerebral ischemia. Mammalian target of rapamycin (mTOR), a major downstream target of Akt, regulates p...

Monolignol ferulate transferase introduces chemically labile linkages into the lignin backbone.

Science 344(6179) , 90-3, (2014)

Redesigning lignin, the aromatic polymer fortifying plant cell walls, to be more amenable to chemical depolymerization can lower the energy required for industrial processing. We have engineered poplar trees to introduce ester linkages into the lignin polymer...

Ferulic acid suppresses activation of hepatic stellate cells through ERK1/2 and Smad signaling pathways in vitro.

Biochem. Pharmacol. 93(1) , 49-58, (2015)

Hepatic stellate cells (HSCs) are the primary source of matrix components in hepatic fibrosis. Ferulic acid (FA) has antifibrotic potential in renal and cardiac disease. However, whether FA comprises inhibitive effects of HSCs activation remains to be clarifi...

Feruloyl glycerol and 1,3-diferuloyl glycerol antioxidant behavior in phospholipid vesicles.

Chem. Phys. Lipids 195 , 11-Jan, (2016)

Feruloyl-sn-glycerol (FG) and 1,3-diferuloyl-sn-glycerol (F2G), the by-product of biocatalytic transesterification soybean oil and ethyl ferulate, were examined for their behavior in phospholipid vesicles. Based on absorbance and fluorescence methods, FG and ...