Nafcillin sodium salt monohydrate

Nafcillin sodium salt monohydrate Structure
Nafcillin sodium salt monohydrate structure
Common Name Nafcillin sodium salt monohydrate
CAS Number 7177-50-6 Molecular Weight 454.472
Density 1.42 g/cm3 Boiling Point 714.1ºC at 760 mmHg
Molecular Formula C21H23N2NaO6S Melting Point N/A
MSDS Chinese USA Flash Point 385.7ºC
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Danger

Effect of NaCl and nafcillin on penicillin-binding protein 2a and heterogeneous expression of methicillin resistance in Staphylococcus aureus.

Antimicrob. Agents Chemother. 31 , 1982-1988, (1987)

Expression of methicillin resistance in heterogeneous strains of Staphylococcus aureus is enhanced by 2 to 5% NaCl in the medium and by selection with beta-lactam antibiotics. Resistance is associated with production of a penicillin-binding protein (PBP), PBP...

Co-trimoxazole versus nafcillin in the therapy of experimental meningitis due to Staphylococcus aureus.

J. Antimicrob. Chemother. 19 , 647-658, (1987)

Co-trimoxazole was compared with nafcillin against Staphylococcus aureus in vitro and in the therapy of experimental Staph. aureus meningitis in rabbits. Co-trimoxazole (trimethoprim:sulphamethoxazole in a 1:20 ratio) was synergistic against 22/24 strains of ...