DL-m-Tyrosine
DL-m-Tyrosine structure
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Common Name | DL-m-Tyrosine | ||
|---|---|---|---|---|
| CAS Number | 775-06-4 | Molecular Weight | 181.189 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 387.2±32.0 °C at 760 mmHg | |
| Molecular Formula | C9H11NO3 | Melting Point | 280-285 °C (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | 188.0±25.1 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Pleiotropic physiological consequences of feedback-insensitive phenylalanine biosynthesis in Arabidopsis thaliana.
Plant J. 63(5) , 823-35, (2010) A large proportion of plant carbon flow passes through the shikimate pathway to phenylalanine, which serves as a precursor for numerous secondary metabolites. To identify new regulatory mechanisms affecting phenylalanine metabolism, we isolated Arabidopsis th... |
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Concomitant tumor resistance: the role of tyrosine isomers in the mechanisms of metastases control.
Cancer Res. 72(5) , 1043-50, (2012) Concomitant tumor resistance (CR) is a phenomenon in which a tumor-bearing host is resistant to the growth of secondary tumor implants and metastasis. Although previous studies indicated that T-cell-dependent processes mediate CR in hosts bearing immunogenic ... |
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Inhibitory effect of a two day fast on reactive oxygen species (ROS) generation by leucocytes and plasma ortho-tyrosine and meta-tyrosine concentrations.
J. Clin. Endocrinol. Metab. 86(6) , 2899-902, (2001) ABSTRACT Since glucose intake acutely increases reactive oxygen species (ROS) generation by polymorphonuclear leucocytes (PMN) and mononuclear cells (MNC), we have now investigated whether a fast over a period of 48h reduces ROS generation by these cells. Eig... |
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Tyrosine isomers mediate the classical phenomenon of concomitant tumor resistance.
Cancer Res. 71(22) , 7113-24, (2011) Concomitant tumor resistance (CR) is a phenomenon originally described in 1906 in which a tumor-bearing host is resistant to the growth of secondary tumor implants and metastasis. Although recent studies have indicated that T-cell-dependent processes mediate ... |
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Quantitative determination of ortho- and meta-tyrosine as biomarkers of protein oxidative damage in beta-thalassemia.
Redox Rep. 12(5) , 219-28, (2007) Oxidative stress in thalassemia is caused by secondary iron overload and stems from blood transfusion and increased iron uptake. In this study, we hypothesized that levels of o- and m-tyrosine, products of hydroxyl radical attack on phenylalanine, would be el... |
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Accumulation of the hydroxyl free radical markers meta-, ortho-tyrosine and DOPA in cataractous lenses is accompanied by a lower protein and phenylalanine content of the water-soluble phase.
Free Radic. Res. 39(12) , 1359-66, (2005) Post-translational modifications of lens proteins play a crucial role in the formation of cataract during ageing. The aim of our study was to analyze protein composition of the cataractous lenses by electrophoretic and high-performance liquid chromatographic ... |
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Nadolol inhibits reactive oxygen species generation by leukocytes and linoleic acid oxidation.
Am. J. Cardiol. 86(4) , 443-8, (2000) We studied the effect of short-term nadolol administration on the reactive oxygen species (ROS) generation by polymorphonuclear leukocytes and mononuclear cells in 8 normal subjects. At a oral dose of 40 mg/day for 5 days, nadolol produced a decrease in the R... |
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Identification of irradiated meats by determining o- and m-tyrosine as markers.
Meat Science 93(2) , 226-32, (2013) To identify the irradiated meats, various parameters that affect extraction efficiency of tyrosine positional isomers were evaluated. The optimum procedure employed simple extraction by 0.1% formic acid and protein precipitation by acetone. Baseline separatio... |
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Eukaryotic cytosolic and mitochondrial phenylalanyl-tRNA synthetases catalyze the charging of tRNA with the meta-tyrosine.
Proc. Natl. Acad. Sci. U. S. A. 106 , 11045-11048, (2009) The accumulation of proteins damaged by reactive oxygen species (ROS), conventionally regarded as having pathological potentials, is associated with age-related diseases such as Alzheimer's, atherosclerosis, and cataractogenesis. Exposure of the aromatic amin... |
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Measurements of protein carbonyls, ortho- and meta-tyrosine and oxidative phosphorylation complex activity in mitochondria from young and old rats.
Free Radic. Biol. Med. 31(2) , 181-90, (2001) Mitochondrial bioenergetic function is often reported to decline with age and the accumulation of oxidative damage is thought to contribute. However, there are considerable uncertainties about the amount and significance of mitochondrial oxidative damage in a... |