1,1,1-trifluoro-5,5-dimethyl-2,4-hexanedione

1,1,1-trifluoro-5,5-dimethyl-2,4-hexanedione Structure
1,1,1-trifluoro-5,5-dimethyl-2,4-hexanedione structure
Common Name 1,1,1-trifluoro-5,5-dimethyl-2,4-hexanedione
CAS Number 22767-90-4 Molecular Weight 196.16700
Density 1.129 g/mL at 25 °C(lit.) Boiling Point 138-141 °C(lit.)
Molecular Formula C8H11F3O2 Melting Point 68-71 ℃/6mm
MSDS Chinese USA Flash Point 105 °F
Symbol GHS02
GHS02
Signal Word Warning

A new sequencing approach for N-unsubstituted heparin/heparan sulfate oligosaccharides.

Glycobiology 25 , 714-25, (2015)

The rare N-unsubstituted glucosamine (GlcNH(3)(+)) residues in heparan sulfate (HS) have important biological and pathophysiological roles. Because of their low natural abundance, the use of chemically generated, structurally defined, N-unsubstituted heparin/...

ROP and ATRP Fabricated Dual Targeted Redox Sensitive Polymersomes Based on pPEGMA-PCL-ss-PCL-pPEGMA Triblock Copolymers for Breast Cancer Therapeutics.

ACS Appl. Mater. Interfaces 7 , 9211-27, (2015)

To minimize cardiotoxicity and to increase the bioavailability of doxorubicin, polymersomes based on redox sensitive amphiphilic triblock copolymer poly(polyethylene glycol methacrylate)-poly(caprolactone)-s-s-poly(caprolactone)-poly(polyethylene glycol metha...

Mechanism of scrapie prion precipitation with phosphotungstate anions.

ACS Chem. Biol. 10 , 1269-77, (2015)

The phosphotungstate anion (PTA) is widely used to facilitate the precipitation of disease-causing prion protein (PrP(Sc)) from infected tissue for applications in structural studies and diagnostic approaches. However, the mechanism of this precipitation is n...

LC-MS/MS method for the determination of two metabolites of tribendimidine, deacylated amidantel and its acetylated metabolite in plasma, blood and dried blood spots.

J. Pharm. Biomed. Anal. 105 , 163-73, (2015)

Tribendimidine has emerged as potential alternative to praziquantel in the treatment of Opisthorchis viverrini infections. To support its clinical development program, a quantitative high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS)...

A novel approach for high sensitive determination of sulfur mustard by derivatization and isotope-dilution LC-MS/MS analysis.

Talanta 132 , 245-51, (2014)

A new isotope-dilution liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for determination of sulfur mustard (SM) has been developed using a direct chemical derivatization method by nucleophile potassium thioacetate (PTA) in aqueous solution. T...

Observation of tissues in open aqueous solution by atmospheric scanning electron microscopy: applicability to intraoperative cancer diagnosis.

Int. J. Oncol. 46(5) , 1872-82, (2015)

In the atmospheric scanning electron microscope (ASEM), a 2- to 3-µm layer of the sample resting on a silicon nitride-film window in the base of an open sample dish is imaged, in liquid, at atmospheric pressure, from below by an inverted SEM. Thus, the time-c...

Production and Purification of Secretory Simian Cytidine Monophosphate-N-acetylneuraminic Acid Hydroxylase Using Baculovirus-Protein Expression System.

Biol. Pharm. Bull. 38 , 1220-6, (2015)

Cytidine monophosphate (CMP) N-acetylneuraminic acid (Neu5Ac) hydroxylase (CMAH) is an essential enzyme for N-glycolylneuraminic acid (Neu5Gc) synthesis. In humans, Neu5Gc cannot be synthesized because of a deletion in the CMAH gene. Since Neu5Gc research has...

An immunohistochemical analysis to validate the rationale behind the enhanced immunogenicity of D-ribosylated low density lipo-protein.

PLoS ONE 9(11) , e113144, (2014)

Advanced glycation end products (AGEs) are thought to contribute to the abnormal lipoprotein profiles and increased risk of cardiovascular disease in patients with diabetes and renal failure. D-ribose is one of the naturally occurring pentose monosaccharide p...

Hydroxyl functionalized polytriazole-co-polyoxadiazole as substrates for forward osmosis membranes.

ACS Appl. Mater. Interfaces 7(7) , 3960-73, (2015)

Hydroxyl functionalized polytriazole-co-polyoxadiazole (PTA-POD) copolymers have been synthesized and cast as promising highly thermally stable, chemically resistant, and antiorganic/biological fouling porous substrates for the fabrication of thin-film compos...

Antibody-opsonized bacteria evoke an inflammatory dendritic cell phenotype and polyfunctional Th cells by cross-talk between TLRs and FcRs.

J. Immunol. 194(4) , 1856-66, (2015)

During secondary immune responses, Ab-opsonized bacteria are efficiently taken up via FcRs by dendritic cells. We now demonstrate that this process induces cross-talk between FcRs and TLRs, which results in synergistic release of several inflammatory cytokine...