7-Aminoflunitrazepam

7-Aminoflunitrazepam Structure
7-Aminoflunitrazepam structure
Common Name 7-Aminoflunitrazepam
CAS Number 34084-50-9 Molecular Weight 283.300
Density 1.3±0.1 g/cm3 Boiling Point 540.3±50.0 °C at 760 mmHg
Molecular Formula C16H14FN3O Melting Point N/A
MSDS N/A Flash Point 280.6±30.1 °C
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger

Long-term stability of various drugs and metabolites in urine, and preventive measures against their decomposition with special attention to filtration sterilization.

Forensic Sci. Int. 174(2-3) , 189-96, (2008)

The long-term stability of drugs and metabolites of forensic interest in urine, and preventive measures against their decomposition have been investigated, with special attention to filtration sterilization. An aseptic urine collection kit, which was recently...

Simultaneous analysis of some club drugs in whole blood using solid phase extraction and gas chromatography-mass spectrometry.

J. Forensic Leg. Med. 19(2) , 77-82, (2012)

The use of psychoactive substances to improve social relations and increase body energy, in Rave Culture, has raised many legal and health public concerns, both for illicit trade and consumption. Therefore, forensic toxicology plays an important role in this ...

A rapid UPLC-MS/MS method for simultaneous determination of flunitrazepam, 7-aminoflunitrazepam, methadone and EDDP in human, rat and rabbit plasma.

Talanta 99 , 649-59, (2012)

A simple, high-throughput, sensitive LC-ESI-MS/MS method is presented for the simultaneous determination of methadone (MET), flunitrazepam (FNZ) and their major metabolites, EDDP (2-ethilidene-1,5-dimethyl-3,3-diphenylpyrrolidone) and 7-aminoflunitrazepam (7-...

The detection of various opiates and benzodiazepines by comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry.

Rapid Commun. Mass Spectrom. 23(3) , 340-8, (2009)

A technique using comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry (GC x GC/TOFMS) is applied to qualitative and quantitative drug testing. Human serum was 'spiked' with known quantities of benzodiazepines and a 'street heroin...

Simultaneous determination and quantification of 12 benzodiazepines in serum or whole blood using UPLC/MS/MS.

Methods Mol. Biol. 603 , 107-19, (2010)

The benzodiazepines are a large, commonly prescribed family of psychoactive drugs. We describe a method permitting the simultaneous detection and quantification of 12 benzodiazepines in serum using ultra-performance liquid chromatography (UPLC) coupled with t...

Acute intoxication caused by overdose of flunitrazepam and triazolam: high concentration of metabolites detected at autopsy examination.

Am. J. Forensic Med. Pathol. 33(4) , 293-6, (2012)

A 52-year-old woman was found dead on the floor of the living room on the first floor of a house, which belonged to the man with whom she shared the house. On visiting the site, her clothes were found to be undisturbed. Packages of flunitrazepam (Silece, 2 mg...

Segmental hair analysis can demonstrate external contamination in postmortem cases.

Forensic Sci. Int. 215(1-3) , 73-6, (2012)

Excluding laboratory mistakes, a false positive hair result can be observed in case of contamination from environmental pollution (external contamination) or after drug incorporation into the hair from the individual body fluids, such as sweat or putrefactive...

Deposition of 7-aminoflunitrazepam and flunitrazepam in hair after a single dose of Rohypnol.

J. Forensic Sci. 46(5) , 1143-51, (2001)

In recent years, there has been a notable increase in the number of reports on drug-facilitated sexual assault. Benzodiazepines are the most common so-called "date-rape" drugs, with flunitrazepam (Rohypnol) being one of the most frequently mentioned. The aim ...

Improved screen and confirmation test of 7-aminoflunitrazepam in urine specimens for monitoring flunitrazepam (Rohypnol) exposure.

J. Anal. Toxicol. 26(7) , 411-8, (2002)

Confirmed and alleged misuses of flunitrazepam (FM2, Rohypnol) have brought about serious interest in the development of an analytical methodology that can be effectively used for preliminary screen and confirmatory test of FM2 (or its metabolites) in urine s...

Performance characteristics of 7-aminoflunitrazepam specific enzyme-linked immunosorbent assays.

J. Anal. Toxicol. 29(7) , 718-23, (2005)

With 7-aminoflunitrazepam (7-amino-FM2)-specific ELISAs now readily available from several commercial sources (e.g., Cozart Bioscience, Immunalysis, this study was conducted to evaluate the performance characteristics of these products when applied to the two...