2-Mercaptopropionic acid

2-Mercaptopropionic acid Structure
2-Mercaptopropionic acid structure
Common Name 2-Mercaptopropionic acid
CAS Number 79-42-5 Molecular Weight 106.14400
Density 1.196 g/mL at 25 °C(lit.) Boiling Point 102 °C16 mm Hg(lit.)
Molecular Formula C3H6O2S Melting Point 10-14 °C(lit.)
MSDS Chinese USA Flash Point 190 °F
Symbol GHS05
GHS05
Signal Word Danger

Mechanistic Scrutiny Identifies a Kinetic Role for Cytochrome b5 Regulation of Human Cytochrome P450c17 (CYP17A1, P450 17A1).

PLoS ONE 10 , e0141252, (2015)

Cytochrome P450c17 (P450 17A1, CYP17A1) is a critical enzyme in the synthesis of androgens and is now a target enzyme for the treatment of prostate cancer. Cytochrome P450c17 can exhibit either one or two physiological enzymatic activities differentially regu...

Phosphorescent quantum dots/ethidium bromide nanohybrids based on photoinduced electron transfer for DNA detection.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 140 , 479-83, (2015)

Mercaptopropionic acid-capped Mn-doped ZnS quantum dots/ethidium bromide (EB) nanohybrids were constructed for photoinduced electron transfer (PIET) and then used as a room-temperature phosphorescence (RTP) probe for DNA detection. EB could quench the RTP of ...

The effect of phosphate on the nuclease activity of vanadium compounds.

J. Inorg. Biochem. 147 , 165-76, (2015)

The nuclease activity of VO(acac)2 (1, acac = acetylacetone) and its derivatives VO(hd)2 (2, hd = 3,5-heptanedione), VO(Cl-acac)2 (3, Cl-acac = 3-chloro-2,4-pentanedione), VO(Et-acac)2 (4, Et-acac = 3-ethyl-2,4-pentanedione) and VO(Me-acac)2 (5, Me-acac = 3-m...

Interaction of digestive enzymes with tunable light emitting quantum dots: a thorough Spectroscopic investigation.

Luminescence 30 , 978-89, (2015)

In this article, we have examined the direct spectroscopic and microscopic evidence of efficient quantum dots-α-chymotrypsin (ChT) interaction. The intrinsic fluorescence of digestive enzyme is reduced in the presence of quantum dots through ground-state comp...

Analyses of functional polymer-modified nanoparticles for protein sensing by surface-assisted laser desorption/ionization mass spectrometry coupled with HgTe nanomatrices.

Colloids Surf. B Biointerfaces 130 , 157-63, (2015)

In this study, we employed HgTe nanostructure-based matrices (nanomartrices; NMs) for surface-assisted laser desorption/ionization mass spectrometry (SALDI-MS) for the analyses of polyethylene glycol (PEG) derivatives as well as thiol-PEG-modified gold nanopa...

Glucose cryoprotectant affects glutathione-responsive antitumor drug release from polysaccharide nanoparticles.

Eur. J. Pharm. Biopharm. 93 , 281-92, (2015)

The aim of this work was to prepare polysaccharide-based nanoparticles (NPs) sensitive to glutathione (GSH), and to elucidate the effect of the concentration of glucose used as cryoprotectant during freeze-drying on the GSH-responsiveness. NPs were obtained v...

Simple and sensitive progesterone detection in human serum using a CdSe/ZnS quantum dot-based direct binding assay.

Anal. Biochem. 483 , 54-61, (2015)

In this study, we developed a CdSe/ZnS quantum dot (QD)-based immunoassay for use in determining the presence of progesterone (P4) in human serum. Hydrophilic QDs were conjugated to anti-progesterone antibody (P4Ab) via ethyl-3-(dimethylaminopropyl)carbodiimi...

Highly luminescent and cytocompatible cationic Ag2S NIR-emitting quantum dots for optical imaging and gene transfection.

Nanoscale 7 , 11352-62, (2015)

The development of non-toxic theranostic nanoparticles capable of delivering a therapeutic cargo and providing a means for diagnosis is one of the most challenging tasks in nano-biotechnology. Gene therapy is a very important mode of therapy and polyethylenei...

Combined nitric oxide-releasing poly(vinyl alcohol) film/F127 hydrogel for accelerating wound healing.

Colloids Surf. B Biointerfaces 130 , 182-91, (2015)

Nitric oxide (NO) releasing biomaterials represent a potential strategy for use as active wound dressings capable of accelerating wound healing. Topical NO-releasing poly(vinyl alcohol) (PVA) films and Pluronic F127 hydrogels (F127) have already exhibited eff...

Emission tunable, cyto/hemocompatible, near-IR-emitting Ag2S quantum dots by aqueous decomposition of DMSA.

Nanoscale 6(20) , 11921-31, (2014)

Size tunable aqueous Ag2S quantum dots emitting in the near-infrared region were synthesized through decomposition of meso-2,3-dimercaptosuccinic acid (DMSA) in water. The resulting NIR QDs are highly cyto- and hemocompatible, have quantum yields as high as 6...