3,3-Dimethylacrylic acid
3,3-Dimethylacrylic acid structure
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Common Name | 3,3-Dimethylacrylic acid | ||
|---|---|---|---|---|
| CAS Number | 541-47-9 | Molecular Weight | 100.116 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 194.5±0.0 °C at 760 mmHg | |
| Molecular Formula | C5H8O2 | Melting Point | 65-70 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 95.9±9.6 °C | |
| Symbol |
GHS05, GHS07 |
Signal Word | Danger | |
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Chemically engineering ligand selectivity at the free fatty acid receptor 2 based on pharmacological variation between species orthologs.
FASEB J. 26 , 4951-65, (2012) When it is difficult to develop selective ligands within a family of related G-protein-coupled receptors (GPCRs), chemically engineered receptors activated solely by synthetic ligands (RASSLs) are useful alternatives for probing receptor function. In the pres... |
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Structure-activity relationships of trans-substituted-propenoic acid derivatives on the nicotinic acid receptor HCA2 (GPR109A).
Bioorg. Med. Chem. Lett. 21 , 2736-9, (2011) Nicotinic acid (niacin) has been used for decades as an antidyslipidemic drug in man. Its main target is the hydroxy-carboxylic acid receptor HCA2 (GPR109A), a G protein-coupled receptor. Other acids and esters such as methyl fumarate also interact with the r... |
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Tritium-labelled isovaleryl-RYYRIK-NH2 as potential antagonist probe for ORL1 nociceptin receptor.
Bioorg. Med. Chem. 22(21) , 5902-9, (2014) IsoVa-RYYRIK-NH2 is a highly specific antagonist ligand of the opioid receptor-like 1 (ORL1) receptor, an endogenous ligand of which is 17-mer peptide nociceptin. ORL1 antagonists have potential for clinical use as analgesic and antineuropathic drugs, and thu... |
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Organic acid excretion in a patient with 3-hydroxy-3-methylglutaryl-CoA lyase deficiency: facts and artefacts.
Clin. Chim. Acta 90(2) , 187-93, (1978) The organic acid excretion in a patient with 3-hydroxy-3-methylglutaryl-CoA lyase deficiency is described. In addition to 3-hydroxy-3-methylglutaric, 3-methylglutaconic, 3-methylglutaric and 3-hydroxyisovaleric acids, substantial amounts of glutaric and adipi... |
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3-methyl-3-butenoic acid: an artefact in the urinary metabolic pattern of patients with 3-hydroxy-3-methylglutaryl-CoA lyase deficiency.
Clin. Chim. Acta 106(1) , 85-9, (1980)
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Beta-methylcrotonic aciduria associated with lactic acidosis.
J. Pediatr. 88(2) , 229-35, (1976) A patient is described in whom lactic acidosis of very severe degree was found to coincide with the presence of beta-methylcrotonic acid and rho-hydroxyphenyllactic acid in urine in large amounts, while beta-hydroxyisovaleric acid was found to be a relatively... |