Acetyl-Amyloid β-Protein (15-20) amide trifluoroacetate salt
Acetyl-Amyloid β-Protein (15-20) amide trifluoroacetate salt structure
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Common Name | Acetyl-Amyloid β-Protein (15-20) amide trifluoroacetate salt | ||
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| CAS Number | 189064-06-0 | Molecular Weight | 822.99000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C42H62N8O9 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
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Arrest of beta-amyloid fibril formation by a pentapeptide ligand.
J. Biol. Chem. 271 , 8545-8548, (1996) Polymerization of amyloid beta-peptide (Abeta) into amyloid fibrils is a critical step in the pathogenesis of Alzheimer's disease. Here, we show that peptides incorporating a short Abeta fragment (KLVFF; Abeta16-20) can bind full-length Abeta and prevent its ... |
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Controlling amyloid beta-peptide fibril formation with protease-stable ligands.
J. Biol. Chem. 272 , 12601-12605, (1997) We have previously shown that short peptides incorporating the sequence KLVFF can bind to the approximately 40amino acid residue Alzheimer amyloid beta-peptide (Abeta) and disrupt amyloid fibril formation (Tjernberg, L. O., Näslund, J., Lindqvist, F., Johanss... |
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