2-fluoro-4-methyl-aniline
2-fluoro-4-methyl-aniline structure
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Common Name | 2-fluoro-4-methyl-aniline | ||
|---|---|---|---|---|
| CAS Number | 452-80-2 | Molecular Weight | 125.144 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 196.5±0.0 °C at 760 mmHg | |
| Molecular Formula | C7H8FN | Melting Point | 3 °C | |
| MSDS | Chinese USA | Flash Point | 79.4±0.0 °C | |
| Symbol |
GHS06 |
Signal Word | Danger | |
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Synthesis of chiral building blocks for use in drug discovery.
Molecules 9(6) , 405-26, (2004) In the past decade there has been a significant growth in the sales of pharmaceutical drugs worldwide, but more importantly there has been a dramatic growth in the sales of single enantiomer drugs. The pharmaceutical industry has a rising demand for chiral in... |
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Rat liver microsomal metabolism of 2-halogenated 4-methylanilines.
Xenobiotica 22(12) , 1403-23, (1992) 1. Rat liver microsomal metabolism of 2-fluoro-, 2-chloro- and 2-bromo-4-methylaniline was investigated using h.p.l.c. Metabolites identified include products from side-chain C-hydroxylation (benzyl alcohols and benzaldehydes) and N-hydroxylation (hydroxylami... |
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Indoline derivatives as 5-HT(2C) receptor agonists.
Bioorg. Med. Chem. Lett. 14 , 2367-2370, (2004) A series of 1-(1-indolinyl)-2-propylamines was synthesised and evaluated as 5-HT(2C) receptor agonists for the treatment of obesity. The general methods of synthesis of the precursor indoles are described. The functional efficacy and radioligand binding data ... |