3-Fluorobenzoic acid
3-Fluorobenzoic acid structure
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Common Name | 3-Fluorobenzoic acid | ||
|---|---|---|---|---|
| CAS Number | 455-38-9 | Molecular Weight | 140.11 | |
| Density | 1.474 | Boiling Point | 251.1ºC at 760mmHg | |
| Molecular Formula | C7H5FO2 | Melting Point | 122-124 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 105.7ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Novel prodrugs of alkylating agents derived from 2-fluoro- and 3-fluorobenzoic acids for antibody-directed enzyme prodrug therapy.
J. Med. Chem. 37(15) , 2361-70, (1994) The synthesis of six novel fluorinated potential prodrugs for antibody-directed enzyme prodrug therapy is described. The [2- and 3-fluoro-4-[bis(2-chloroethyl)amino]benzoyl]-L-glutamic acid (9 and 21), their bis(mesyloxy)ethyl derivatives (7 and 19), and thei... |
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Metabolism of monofluoro- and monochlorobenzoates by a dentrifying bacterium.
Arch. Microbiol. 122(3) , 301-6, (1979)
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19F-NMR study on the interaction of fluorobenzoate with porcine kidney D-amino acid oxidase.
J. Biochem. 105(2) , 318-22, (1989) The interactions of competitive inhibitors, o-, m-, and p-fluorobenzoates, with porcine kidney D-amino acid oxidase (DAO) were studied by 19F-NMR spectroscopy. The 19F-signals of DAO-bound fluorobenzoates were observed as considerably broadened peaks. The che... |
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Generation of a catR deficient mutant of P. putida KT2440 that produces cis, cis-muconate from benzoate at high rate and yield.
J. Biotechnol. 156(3) , 163-72, (2011) Pseudomonas putida KT2440-JD1 was derived from P. putida KT2440 after N-methyl-N'-nitro-N-nitrosoguanidine (NTG)-mutagenesis and exposure to 3-fluorobenzoate (3-FB). The mutant was no longer able to grow using benzoate as a sole carbon source, but co-metaboli... |
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A 19F NMR study of fluorobenzoate biodegradation by Sphingomonas sp. HB-1.
FEMS Microbiol. Lett. 237(2) , 355-61, (2004) While several microorganisms readily degrade 2- and 4-fluorobenzoates, only a very small number appear to catabolise the 3-fluoro isomer, owing to the accumulation of toxic intermediates. Here we describe the isolation of a bacterium capable of using 3-fluoro... |
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Metabolism of hydroxylated and fluorinated benzoates by Syntrophus aciditrophicus and detection of a fluorodiene metabolite.
Appl. Environ. Microbiol. 75(4) , 998-1004, (2009) Transformations of 2-hydroxybenzoate and fluorobenzoate isomers were investigated in the strictly anaerobic Syntrophus aciditrophicus to gain insight into the initial steps of the metabolism of aromatic acids. 2-Hydroxybenzoate was metabolized to methane and ... |