2-Fluorobenzoic acid
2-Fluorobenzoic acid structure
|
Common Name | 2-Fluorobenzoic acid | ||
|---|---|---|---|---|
| CAS Number | 445-29-4 | Molecular Weight | 140.11 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 244.7±13.0 °C at 760 mmHg | |
| Molecular Formula | C7H5FO2 | Melting Point | 122-125 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 101.8±19.8 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
|
Degradation of 2-bromo-, 2-chloro- and 2-fluorobenzoate by Pseudomonas putida CLB 250.
FEMS Microbiol. Lett. 51(1) , 143-7, (1989) Pseudomonas putida strain CLB 250 (DSM 5232) utilized 2-bromo-, 2-chloro- and 2-fluorobenzoate as sole source of carbon and energy. Degradation is suggested to be initiated by a dioxygenase liberating halide in the first catabolic step. After decarboxylation ... |
|
|
The preparation of zaragozic acid A analogues by directed biosynthesis.
J. Antibiot. 47(11) , 1290-4, (1994) Zaragozic acid A analogues are produced by an unidentified sterile fungus when it is exogenously supplied with 2-thiophenecarboxylic acid, 3-thiophenecarboxylic acid, 2-furoic acid, 2-fluorobenzoic acid, 3-fluorobenzoic acid, or 4-fluorobenzoic acid. The anal... |
|
|
Titration of nonstabilized diazoalkane solutions by fluorine NMR.
J. Org. Chem. 77(2) , 1181-5, (2012) A new protocol for titrating nonstabilized diazoalkane solutions by quantitative (19)F NMR is reported. An excess of 2-fluorobenzoic acid dissolved in CDCl(3) is treated with the diazoalkane solution at a low temperature, immediately forming the corresponding... |
|
|
Microbial degradation of synthetic organochlorine compounds.
Experientia 39(11) , 1214-20, (1983)
|
|
|
Novel prodrugs of alkylating agents derived from 2-fluoro- and 3-fluorobenzoic acids for antibody-directed enzyme prodrug therapy.
J. Med. Chem. 37(15) , 2361-70, (1994) The synthesis of six novel fluorinated potential prodrugs for antibody-directed enzyme prodrug therapy is described. The [2- and 3-fluoro-4-[bis(2-chloroethyl)amino]benzoyl]-L-glutamic acid (9 and 21), their bis(mesyloxy)ethyl derivatives (7 and 19), and thei... |
|
|
Preparation of F-18 labeled annexin V: a potential PET radiopharmaceutical for imaging cell death.
Nucl. Med. Biol. 31(6) , 747-52, (2004) The clinical response to antitumor therapy is measured using imaging, such as CT or MRI, 6-12 weeks following chemotherapy treatment. The images at that time reflect both tumor cell death and new growth. Therefore, the amount of tumor cell death caused by che... |
|
|
Biodegradation of 2-fluorobenzoate and dichloromethane under simultaneous and sequential alternating pollutant feeding.
Water Res. 42(14) , 3857-69, (2008) Two up-flow fixed-bed reactors (UFBRs), inoculated with activated sludge and operated for 162 days, were fed 1mmolL(-1)d(-1) with two model halogenated compounds, 2-fluorobenzoate (2-FB) and dichloromethane (DCM). Expanded clay (EC) and granular activated car... |
|
|
Isolation and properties of a pure bacterial strain capable of fluorobenzene degradation as sole carbon and energy source.
Environ. Microbiol. 7(2) , 294-8, (2005) A pure bacterial strain capable of aerobic biodegradation of fluorobenzene (FB) as the sole carbon and energy source was isolated by selective enrichment from sediments collected from a polluted site. 16S rRNA and fatty acid analyses support that strain F11 b... |
|
|
Anaerobic degradation of 2-fluorobenzoate by benzoate-degrading, denitrifying bacteria.
J. Bacteriol. 161(1) , 321-5, (1985) Three strains of anaerobically benzoate-degrading, denitrifying bacteria of the genus Pseudomonas were able to grow on 2-fluorobenzoate as the sole carbon and energy source. Fluoride ion release was stoichiometric, and the reduction of dissolved organic carbo... |
|
|
A simple and efficient in vitro method for metabolism studies of radiotracers.
Nucl. Med. Biol. 28(4) , 391-5, (2001) In vitro metabolism of acetylcholinesterase inhibitors containing 3-[(18)F]fluoromethylbenzyl- ([(18)F]1) and 4-[(18)F]fluorobenzyl-piperidine moieties ([(18)F]2) was studied and compared with the in vivo metabolism. Defluorination of the [(18)F]1 mainly occu... |