Dantron

Dantron Structure
Dantron structure
Common Name Dantron
CAS Number 117-10-2 Molecular Weight 240.211
Density 1.5±0.1 g/cm3 Boiling Point 452.7±35.0 °C at 760 mmHg
Molecular Formula C14H8O4 Melting Point 191-193 °C(lit.)
MSDS Chinese USA Flash Point 241.7±22.4 °C
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Warning

Safety assessment of dietary bamboo charcoal powder: a 90-day subchronic oral toxicity and mutagenicity studies.

Food Chem. Toxicol. 75 , 50-7, (2015)

Vegetable carbon has been used as food additive in EU (E153) and China for many years; however, no experimental data have been available on its dietary safety. This study was designed to evaluate the subchronic toxicity and genotoxicity of bamboo charcoal pow...

Determination of hydroxylated polycyclic aromatic hydrocarbons by HPLC-photoionization tandem mass spectrometry in wood smoke particles and soil samples.

Anal. Bioanal. Chem 407 , 4523-34, (2015)

A simple and fast method for analysis of hydroxylated polycyclic aromatic hydrocarbons using pressurized liquid extraction and high performance liquid chromatography utilizing photoionization tandem mass spectrometry was developed. Simultaneous separation and...

1,4-dihydroxyanthraquinone electrochemical sensor based on molecularly imprinted polymer using multi-walled carbon nanotubes and multivariate optimization method.

Talanta 146 , 525-32, (2015)

The present work describes development of a simple and cost-effective electrochemical sensor for determination of 1,4-dihydroxyanthraquinone (1,4-DAQ) based on molecularly imprinted polypyrrole (PPY). The molecularly imprinted polymer (MIP) was electrochemica...

Synchrotron radiation linear dichroism (SRLD) investigation of the electronic transitions of quinizarin, chrysazin, and anthrarufin.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 77(1) , 279-86, (2010)

The electronic transitions of the three alpha,alpha'-dihydroxy derivatives of anthraquinone, 1,4-dihydroxy-, 1,8-dihydroxy-, and 1,5-dihydroxy-9,10-anthraquinone (quinizarin, chrysazin, and anthrarufin), were investigated by synchrotron radiation linear dichr...

DNA-binding, DNA cleavage and cytotoxicity studies of two anthraquinone derivatives.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 87 , 232-40, (2012)

The interaction of native calf thymus DNA (CT-DNA) with two anthraquinones including quinizarin (1,4-dihydroxy anthraquinone) and danthron (1,8-dihydroxy anthraquinone) in a mixture of 0.04M Brittone-Robinson buffer and 50% of ethanol were studied at physiolo...

Anthraquinones danthron and quinizarin exert antiproliferative and antimetastatic activity on murine B16-F10 melanoma cells.

Anticancer Res. 30(2) , 445-9, (2010)

The anticancer potential of anthraquinones danthron and quinizarin on highly metastatic B16-F10 melanoma murine cells was investigated. Several parameters related to cell proliferation and differentiation, i.e. cell number, intracellular content of polyamines...

Reactivity of aromatic amines with triplet 1,8-dihydroxyanthraquinone: a laser flash photolysis study.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 66(1) , 63-7, (2007)

The property of the lowest excited triplet states of 1,8-dihydroxyanthraquinone (DHAQ) was investigated by using time-resolved laser flash photolysis at 355nm in organic solvents, i.e. acetonitrile and cyclohexane. The transient absorption spectra of the exci...

Study of interactions of anthraquinones with DNA using ethidium bromide as a fluorescence probe.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 70(1) , 136-43, (2008)

The interactions of fish sperm deoxyribonucleic acid (DNA) with anthraquinones, such as chrysophanol, physcion and 1,8-dihydroxy anthraquinone, were investigated by using ethidium bromide (EB) as fluorescence probe. The binding constants of anthraquinones and...

Danthron functions as a retinoic X receptor antagonist by stabilizing tetramers of the receptor.

J. Biol. Chem. 286(3) , 1868-75, (2011)

Retinoic X receptor (RXR) is a promising target for drug discovery against cancer and metabolic syndromes. Here, we identified a specific RXRα antagonist, danthron, from the traditional Chinese medicine rhubarb. Danthron repressed all tested RXRα-involved res...

A new dibenz[b,e]oxepine derivative, 1-hydroxy-10-methoxy-dibenz[b,e]oxepin-6,11-dione, from a marine-derived fungus, Beauveria bassiana TPU942.

Mar. Drugs 10(12) , 2691-2697, (2012)

1-Hydroxy-10-methoxy-dibenz[b,e]oxepin-6,11-dione (1) was obtained from the culture broth of a marine-derived fungus, Beauveria bassiana TPU942, isolated from a marine sponge collected at Iriomote Island in Okinawa, together with two known compounds, chrysazi...