phosgene
phosgene structure
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Common Name | phosgene | ||
|---|---|---|---|---|
| CAS Number | 75-44-5 | Molecular Weight | 98.91610 | |
| Density | 0.94 g/mL at 20 °C | Boiling Point | 8.2ºC at 760 mmHg | |
| Molecular Formula | CCl2O | Melting Point | -118ºC | |
| MSDS | Chinese | Flash Point | 4 °C | |
| Symbol |
GHS02, GHS05, GHS06, GHS08 |
Signal Word | Danger | |
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Developmental exposure to purity-controlled polychlorinated biphenyl congeners (PCB74 and PCB95) in rats: effects on brainstem auditory evoked potentials and catalepsy.
Toxicology 327 , 22-31, (2015) Whereas the effects of dioxin-like polychlorinated biphenyls (DL-PCBs) are well described, less is known about non-dioxin-like PCBs (NDL-PCBs), including influences on the nervous system and related behavioral effects after developmental exposure. Following t... |
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One-step synthesis of biodegradable curcumin-derived hydrogels as potential soft tissue fillers after breast cancer surgery.
Biomacromolecules 13(8) , 2279-86, (2012) A one-step synthesis of a curcumin-derived hydrogel (curcumin content of 25-75 mol %) is reported. Curcumin is incorporated into the hydrogel backbone and cross-linked through biodegradable carbonate linkages. Curcumin as a part of the polymer backbone is pro... |
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Radiosynthesis of [13N]dantrolene, a positron emission tomography probe for breast cancer resistant protein, using no-carrier-added [13N]ammonia.
Bioorg. Med. Chem. 20(1) , 305-10, (2012) Dantrolene (1) is a substrate for breast cancer resistant protein, which is widely distributed in the blood-brain-barrier, intestine, gall bladder, and liver. PET study with 1 labeled with a positron emitter can be used to visualize BCRP and to elucidate the ... |
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Acute nose-only inhalation exposure of rats to di- and triphosgene relative to phosgene.
Inhal. Toxicol. 23(2) , 65-73, (2011) Groups of young adult Wistar rats were acutely exposed to trichloromethyl chloroformate (diphosgene) and bis(trichloromethyl) carbonate (triphosgene) vapor atmospheres using a directed-flow nose-only mode of exposure. The exposure duration used was 240 min. T... |
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[An accident of chloroethyl chloroformate poisoning].
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 29(1) , 38, (2011)
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Morphological and functional differentiation in BE(2)-M17 human neuroblastoma cells by treatment with Trans-retinoic acid.
BMC Neurosci. 14 , 49, (2013) Immortalized neuronal cell lines can be induced to differentiate into more mature neurons by adding specific compounds or growth factors to the culture medium. This property makes neuronal cell lines attractive as in vitro cell models to study neuronal functi... |
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Array of Love-wave sensors based on quartz/Novolac to detect CWA simulants.
Talanta 85(3) , 1442-7, (2011) An array of Love-wave sensors based on quartz and Novolac has been developed to detect chemical warfare agents (CWAs). These weapons are a risk for human health due to their efficiency and high lethality; therefore an early and clear detection is of enormous ... |
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Corticosteroids found ineffective for phosgene-induced acute lung injury in rats.
Toxicol. Lett. 229(1) , 85-92, (2014) Various therapeutic regimes have been proposed with limited success for treatment of phosgene-induced acute lung injury (P-ALI). Corticoids were shown to be efficacious against chlorine-induced lung injury but there is still controversy whether this applies a... |
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The methenamine misunderstanding in the therapy of phosgene poisoning.
Arch. Toxicol. 46(3-4) , 199-206, (1980) A thorough analysis of the pertinent literature leads to the conclusion that there is no justification for the use of methenamine (hexamethylene tetramin, Urotropin) for the therapy of phosgene poisoning. |
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Development and validation of a sensitive thermal desorption-gas chromatography-mass spectrometry (TD-GC-MS) method for the determination of phosgene in air samples.
Anal. Bioanal. Chem 406(21) , 5137-45, (2014) A new rapid, sensitive and reliable method was developed for the determination of phosgene in air samples using thermal desorption (TD) followed by gas chromatography-mass spectrometry (GC-MS). The method is based on a fast (10 min) active sampling of only 1 ... |