H-Glu(OEt)-OEt.HCl

H-Glu(OEt)-OEt.HCl Structure
H-Glu(OEt)-OEt.HCl structure
Common Name H-Glu(OEt)-OEt.HCl
CAS Number 1118-89-4 Molecular Weight 239.697
Density 1.08g/cm3 Boiling Point 262ºC at 760 mmHg
Molecular Formula C9H18ClNO4 Melting Point 108-110 °C(lit.)
MSDS Chinese USA Flash Point 86.3ºC

Fast-acting excitatory amino acids are involved in the enhancement of the aversiveness of the electrical stimulation of the inferior colliculus by systemic injections of muscimol.

Life Sci. 71(25) , 2961-72, (2002)

Gradual increases in the electrical stimulation of the inferior colliculus produces progressive aversive responses from vigilance, through freezing, until escape. These responses are probably mediated by excitatory amino acids (EAA) mechanisms as microinjecti...

Glycine increases arterial pressure and augments NMDA-induced pressor responses in the dorsomedial and ventrolateral medulla of cats.

J. Auton. Nerv. Syst. 67(3) , 145-55, (1997)

The present study is designed to determine and characterize two neurobiological events. Firstly, we investigated whether increases of systemic arterial pressure (SAP) and sympathetic vertebral nerve activity (VNA) produced by microinjection of glycine (Gly) i...

Mass spectrometric and kinetic studies on slow progression of papain-catalyzed polymerization of L-glutamic acid diethyl ester.

Biochim. Biophys. Acta 1780(6) , 881-91, (2008)

Papain polymerizes L-glutamic acid diethyl ester (Glu-di-OEt) regioselectively, resulting in the formation of poly (gamma-ethyl alpha-L-glutamic acid) with various degrees of polymerization of less than 13. Reaction temperatures below 20 degrees C were approp...

Neurotransmitters in the thalamus relaying visceral input to the insular cortex in the rat.

Am. J. Physiol. Regul. Integr. Comp. Physiol. 281(5) , R1665-74, (2001)

Neurotransmitters relaying ascending visceral information were examined by comparing the response of neurons in the insular cortex to vagal stimulation (0.8 Hz, 2 mA) before and after neurotransmitter antagonist injections (200 nl) in the ventroposterior parv...

Synthesis of N-(5,7-diamino-3-phenyl-quinoxalin-2-yl)-3,4,5-substituted anilines and N-[4[(5,7-diamino-3-phenylquinoxalin-2-yl)amino]benzoyl]-l-glutamic acid diethyl ester: evaluation of in vitro anti-cancer and anti-folate activities.

Eur. J. Med. Chem. 43(1) , 189-203, (2008)

Several diamino quinoxalines were designed, synthesized and evaluated as anti-tumor agents. Two compounds showed the most potent cytotoxic activities against the leukemia CCRF-CEM cell line (GI(50)<0.01microM) and the ovarian cancer cell line OVCAR-4 (GI(50)=...

Neonatal glutamate can destroy the hippocampal CA1 structure and impair discrimination learning in rats.

Brain Res. 616(1-2) , 311-4, (1993)

Neonatal Wistar rats were subcutaneously injected with 0.1, 1, or 2 mg/g b.wt. of monosodium glutamate (MSG) at 1, 3, 5, 7, and 9 days after birth. The animals were observed for degeneration of pyramidal cells in the hippocampus. The histological change disap...

Endothelin-1 and endothelin-3 modulate dopaminergic neurons through different mechanisms.

Life Sci. 57(8) , 735-41, (1995)

Novel vasoconstrictor peptides, endothelin-1 (ET-1) and endothelin-3 (ET-3), are also known as neuropeptides or neuromodulators. When either ET-1 or ET-3 was administered to the rat striatum via a microinjection needle, the dopamine release from the striatum ...

Effects of L-glutamate, substance P and substance P(1-7) on cardiovascular regulation in the nucleus tractus solitarius.

Regul. Pept. 46 , 102, (1993)

Inhibition of cocaine intoxication by excitatory amino acid receptor antagonists.

Ann. N. Y. Acad. Sci. 648 , 335-7, (1992)

Cholinergic and glutamatergic transmission in medial vestibular nucleus neurons responding to lateral roll tilt in rats.

Brain Res. 840(1-2) , 99-105, (1999)

The responses of the medial vestibular nucleus (MVN) neurons to lateral tilt and the neurotransmitters mediating otolith information to MVN neurons were investigated using rats. A computer-operated goniometer was tilted 20 degrees clockwise and counterclockwi...