Baicalin
Baicalin structure
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Common Name | Baicalin | ||
|---|---|---|---|---|
| CAS Number | 21967-41-9 | Molecular Weight | 446.361 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 836.6±65.0 °C at 760 mmHg | |
| Molecular Formula | C21H18O11 | Melting Point | 202-205 ºC | |
| MSDS | Chinese USA | Flash Point | 297.2±27.8 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Baicalin inhibits the fenton reaction by enhancing electron transfer from Fe (2+) to dissolved oxygen.
Am. J. Chin. Med. 43(1) , 87-101, (2015) Sho-saiko-to is an herbal medicine that is known to have diverse pharmacological activities and has been used for the treatment of various infectious diseases. Here, we examined the effects of baicalin, a compound isolated from Sho-saiko-to, and the effects o... |
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Involvement of the inhibition of intestinal glucuronidation in enhancing the oral bioavailability of resveratrol by labrasol containing nanoemulsions.
Mol. Pharm. 12(4) , 1084-95, (2015) Nanoemulsions have been developed for the oral delivery of poorly bioavailable phenolic compounds that are sensitive to intestinal glucuronidation. However, little is known about the contribution of UDP-glucuronosyltransferase (UGT) inhibitory excipients in n... |
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Therapeutic effects of baicalin on monocrotaline-induced pulmonary arterial hypertension by inhibiting inflammatory response.
Int. Immunopharmacol. 26 , 188-93, (2015) Baicalin has been shown to possess various pharmacological actions, a recent study revealed that baicalin can attenuate pulmonary hypertension and pulmonary vascular remodeling through the inhibition of pulmonary artery smooth muscle cell proliferation, howev... |
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Extraction and Bioactivity Analysis of Major Flavones Compounds from Scutellaria baicalensis Using In Vitro Assay and Online Screening HPLC-ABTS System.
J. Anal. Methods Chem. 2014 , 563702, (2014) The extraction efficiency of a number of solvent compositions for the improvement of bioactive compounds yield from S. baicalensis has been investigated. Also, free radical scavengers in the glycoside baicalin (BG), wogonoside (WG), aglycon baicalein (B), and... |
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Research Article Flavocoxid Protects Against Cadmium-Induced Disruption of the Blood-Testis Barrier and Improves Testicular Damage and Germ Cell Impairment in Mice.
Toxicol. Sci. 148 , 311-29, (2015) Cadmium (Cd) causes male infertility. There is the need to identify safe treatments counteracting this toxicity. Flavocoxid is a flavonoid that induces a balanced inhibition of cyclooxygenase (COX)-1 and COX-2 peroxidase moieties and of 5-lipoxygenase (LOX) a... |
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Synergistic interactions among flavonoids and acetogenins in Graviola (Annona muricata) leaves confer protection against prostate cancer.
Carcinogenesis 36 , 656-65, (2015) Phytochemical complexity of plant extracts may offer health-promoting benefits including chemotherapeutic and chemopreventive effects. Isolation of 'most-active fraction' or single constituents from whole extracts may not only compromise the therapeutic effic... |
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Study on formability of solid nanosuspensions during solidification: II novel roles of freezing stress and cryoprotectant property.
Int. J. Pharm. 475(1-2) , 35-48, (2014) The freezing stress and cryoprotectants were known to be the crucial factors for solidification formability of nanosuspensions during freeze-drying. However, there has been controversy as to whether an aggressive or conservative freezing stress (freezing temp... |
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AKT serine/threonine protein kinase modulates baicalin-triggered autophagy in human bladder cancer T24 cells.
Int. J. Oncol. 42(3) , 993-1000, (2013) Baicalin is one of the major compounds in the traditional Chinese medicinal herb from Scutellaria baicalensis Georgi. We investigated the molecular mechanisms of cell autophagy induced by baicalin in human bladder cancer T24 cells. Baicalin inhibited cell sur... |
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Quantitative assessment of traditional Oriental herbal formulation Samhwangsasim-tang using UPLC technique.
J. Chromatogr. Sci. 52(2) , 176-85, (2014) A specific and reliable ultra-performance liquid chromatography-diode array detection method has been developed and validated for the quantitative assessment of a traditional Oriental herbal formulation, Samhwangsasim-tang (SST). A Halo reversed-phase amide c... |
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Liquid Chromatography-Tandem Mass Spectrometry Screening Method for the Detection of Radical-Scavenging Natural Antioxidants from the Whole Scutellariae (Radix, Stem and Leaf).
J. Chromatogr. Sci. 53 , 1140-6, (2015) A novel free radical reaction combined with high-performance LC-photodiode array-ESI-MS/MS screening method was developed for the detection and identification of natural antioxidants from whole Scutellariae. Six compounds and whole Scutellariae extracts were ... |