5-Nitro-1,2-dihydroacenaphthylene

5-Nitro-1,2-dihydroacenaphthylene Structure
5-Nitro-1,2-dihydroacenaphthylene structure
Common Name 5-Nitro-1,2-dihydroacenaphthylene
CAS Number 602-87-9 Molecular Weight 199.205
Density 1.4±0.1 g/cm3 Boiling Point 377.5±21.0 °C at 760 mmHg
Molecular Formula C12H9NO2 Melting Point 100-101 °C(lit.)
MSDS Chinese USA Flash Point 191.8±14.9 °C
Symbol GHS08
GHS08
Signal Word Danger

5-Nitroacenaphthene: a newly recognized role for the nitro function in mutagenicity.

Environ. Mutagen. 5(1) , 17-22, (1983)

The direct-acting mutagenicity of 5-nitroacenaphthene for Salmonella typhimurium is dependent upon the reduction of the nitro function as evidenced by the significant decrease in mutagenicity seen with nitroreductase-deficient Salmonella strains. Addition of ...

Identification of mutagenic metabolites formed by C-hydroxylation and nitroreduction of 5-nitroacenaphthene in rat liver.

Cancer Res. 42(4) , 1243-8, (1982)

The metabolism of the mutagen and carcinogen, 5-nitroacenaphthene, by the 9000 x g supernatant from the livers of Aroclor-pretreated rats was studied. The major primary metabolites were 1-hydroxy-5-nitroacenaphthene and 2-hydroxy-5-nitroacenaphthene. These me...