o-Toluidine HCl
o-Toluidine HCl structure
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Common Name | o-Toluidine HCl | ||
|---|---|---|---|---|
| CAS Number | 636-21-5 | Molecular Weight | 143.614 | |
| Density | N/A | Boiling Point | 242 °C | |
| Molecular Formula | C7H10ClN | Melting Point | 215-217 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 85ºC | |
| Symbol |
GHS07, GHS08 |
Signal Word | Danger | |
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Sensitive ionization of non-volatile analytes using protein solutions as spray liquid in desorption electrospray ionization mass spectrometry.
Rapid Commun. Mass Spectrom. 26(23) , 2770-6, (2012) Desorption electrospray ionization (DESI) is the most popular ambient ionization technique for direct analysis of complex samples without sample pretreatment. However, for many applications, especially for trace analysis, it is of interest to improve the sens... |
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Exposure to o-toluidine, aniline, and nitrobenzene in a rubber chemical manufacturing plant: a retrospective exposure assessment update.
J. Occup. Environ. Hyg. 9(8) , 478-90, (2012) The National Institute for Occupational Safety and Health previously conducted a retrospective cancer incidence and mortality study of workers employed at a rubber chemical manufacturing plant. Compared with New York State incidence, the bladder cancer risk w... |
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Exposure of hairdressers to ortho- and meta-toluidine in hair dyes.
Occup. Environ. Med. 72(1) , 57-63, (2015) Carcinogenic aromatic amines derived from hair dyes have recently received new attention. One of these is ortho (o)-toluidine, which is classified as carcinogenic to humans.To clarify exposure of hairdressers to potentially carcinogenic aromatic amines, inclu... |
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Electrochemical copolymerization study of o-toluidine and o-aminophenol by the simultaneous EQCM and in situ FTIR spectroelectrochemistry.
Talanta 81(1-2) , 664-72, (2010) The electrochemical synthesis and characterization of a copolymer, poly(o-toluidine-co-o-aminophenol), were conducted using in situ piezoelectric FTIR spectroelectrochemistry. The monomer feed ratio strongly affects the copolymerization rate and the propertie... |
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DNA adducts of ortho-toluidine in human bladder.
Biomarkers 16(2) , 120-8, (2011) 4-Aminobiphenyl (4-ABP) and o-toluidine are known human bladder carcinogens, but only 4-ABP-releasing DNA adducts are known.Determination of 4-ABP and o-toluidine-releasing DNA adducts in epithelial and submucosal bladder tissues of sudden death victims (SDV:... |
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Determination of 2,5-toluylenediamine (2,5-TDA) and aromatic amines in urine after personal application of hair dyes: kinetics and doses.
Arch. Toxicol. 85(2) , 127-33, (2011) The personal use of hair dye products is currently under discussion due to the potentially increased risk of bladder cancer among long-time users described in epidemiological literature. In order to investigate the dermal absorption of aromatic diamines as we... |
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Self-assembly directed synthesis of poly(ortho-toluidine)-metal(gold and palladium) composite nanospheres.
J. Nanosci. Nanotechnol. 7(9) , 3117-25, (2007) Poly(ortho-toluidine) (POT)-gold (Au) and palladium (Pd) composite nanospheres were successfully synthesized by the reaction of o-toluidine with the corresponding metal (Au or Pd) colloidal solution through self-assembly process in the presence of dodecylbenz... |
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Assessment of the medicines lidocaine, prilocaine, and their metabolites, 2,6-dimethylaniline and 2-methylaniline, for DNA adduct formation in rat tissues.
Drug Metab. Dispos. 36(8) , 1470-5, (2008) The local anesthetics lidocaine (lido) and prilocaine (prilo) are metabolized to their constituent aromatic amines 2,6-dimethylaniline (DMA, 2,6-xylidine) and 2-methylaniline (MA, o-toluidine), respectively, which are both tumorigenic in rats. The capacity of... |
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Establishing a total allowable concentration of o-toluidine in drinking water incorporating early lifestage exposure and susceptibility.
Regul Toxicol Pharmacol 64(2) , 269-84, (2012) o-Toluidine is a monocyclic aromatic amine present in the formulation of some materials that contact drinking water. NSF/ANSI 61 Annex A (2011) and US EPA (2005a) risk assessment guidelines were used to determine an acceptable drinking water level. Occupation... |
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Liver nuclear and microsomal CYP2E1-mediated metabolism of xenobiotics in rats chronically drinking an alcohol-containing liquid diet.
Toxicol. Ind. Health 22(9) , 367-74, (2006) In previous studies from our laboratory, the presence in highly purified liver nuclei of metabolic pathways for processing ethanol (EtOH), N-nitrosodimethylamine (NDMA), carbon tetrachloride and chloroform was reported. All these chemicals are known to be met... |