2-Bromoethanol

2-Bromoethanol Structure
2-Bromoethanol structure
Common Name 2-Bromoethanol
CAS Number 540-51-2 Molecular Weight 124.965
Density 1.7±0.1 g/cm3 Boiling Point 136.2±13.0 °C at 760 mmHg
Molecular Formula C2H5BrO Melting Point -80 °C
MSDS Chinese USA Flash Point 57.1±9.5 °C
Symbol GHS05 GHS06
GHS05, GHS06
Signal Word Danger

Halogenated derivatives QSAR model using spectral moments to predict haloacetic acids (HAA) mutagenicity.

Bioorg. Med. Chem. 16 , 5720-32, (2008)

The risk of the presence of haloacetic acids in drinking water as chlorination by-products and the shortage of experimental mutagenicity data for most of them requires a research work. This paper describes a QSAR model to predict direct mutagenicity for these...

Preparation and mechanism insight of nuclear envelope-like polymer vesicles for facile loading of biomacromolecules and enhanced biocatalytic activity.

ACS Nano 8(7) , 6644-54, (2014)

The facile loading of sensitive and fragile biomacromolecules, such as glucose oxidase, hemoglobin, and ribonucleic acid (RNA), via synthetic vehicles directly in pure aqueous media is an important technical challenge. Inspired by the nucleus pore complex tha...

Determination of three estrogens and bisphenol A by functional ionic liquid dispersive liquid-phase microextraction coupled with ultra-high performance liquid chromatography and ultraviolet detection.

J. Sep. Sci. 38 , 2158-66, (2015)

A hydroxyl-functionalized ionic liquid, 1-hydroxyethyl-3-methylimidazolium bis(trifluoromethanesulfonyl)imide, was employed in an improved dispersive liquid-phase microextraction method coupled with ultra high performance liquid chromatography for the enrichm...

Comparison of the mutagenic potency of 2-chloroethanol, 2-bromoethanol, 1,2-epoxybutane, epichlorohydrin and glycidaldehyde in Klebsiella pneumoniae, Drosophila melanogaster and L5178Y mouse lymphoma cells.

Mutat. Res. 101(3) , 199-208, (1982)

A series of 2 haloethanols and 3 epoxides was investigated in 3 mutagenicity test systems, namely (1) the fluctuation test in Klebsiella pneumoniae, (2) the sex-linked recessive lethal test in Drosophila melanogaster, and (3) the HGPRT test with L5178Y mouse ...

Characterizing the rovibrational distribution of CD2CD2OH radicals produced via the photodissociation of 2-bromoethanol-d4.

J. Phys. Chem. A 115(51) , 14559-69, (2011)

This work characterizes the internal energy distribution of the CD(2)CD(2)OH radical formed via photodissociation of 2-bromoethanol-d(4). The CD(2)CD(2)OH radical is the first radical adduct in the addition of the hydroxyl radical to C(2)D(4) and the product ...

[Carcinogenic activity of ethylene oxide and its reaction products 2-chlorethanol, 2-bromoethanol, ethylene glycol and diethylene glycol. II. Testing of 2-chlorethanol and 2-bromoethanol for carcinogenic activity].

Zentralbl. Bakteriol. Mikrobiol. Hyg. B. 177(3-4) , 269-81, (1983)

The compounds 2-chloroethanol and 2-bromoethanol were administered once weekly subcutaneously to groups of 100 female NMRI mice, in the case of 2-chloroethanol in 3 dosages (3.0, 1.0 and 0.3 mg, single dosage per mouse) and 2-bromoethanol in 2 dosages (1.0 an...

2-Halogeno-ethanols as an uncoupler of phosphorylation in rat liver mitochondria.

Experientia 36(5) , 537-9, (1980)

2-Chloroethanol, 2-bromoethanol and 2,2,2-trifluoroethanol at a concentration of 0.79 vol.% stimulated state 4 respiration and released oligomycin inhibition of state 3 respiration. 2-Fluoroethanol and 1-propanol at the same concentration did not affect the r...

[Carcinogenic activity of ethylene oxide and its reaction products 2-chloroethanol, 2-bromoethanol, ethylene glycol and diethylene glycol. III. Research on ethylene glycol and diethylene glycol for carcinogenic effects].

Zentralbl. Bakteriol. Mikrobiol. Hyg. B. 183(4) , 358-65, (1987)

Ethylene glycol and diethylene glycol were each administered once weekly subcutaneously to groups of 100 female NMRI mice at 3 dosages (30; 10 und 3 mg single dose per mouse). Tricaprylin was used as solvent. The mean total dosage per mouse was 2110.5; 707.0 ...

Active site structural change of alpha-chymotrypsin due to 2-halogeno-ethanols; comparison with ethanol, I-propanol, and urea.

Experientia 36(5) , 534-5, (1980)

2-Halogeno-ethanols change the active site structure of alpha-chymotrypsin more rapidly and effectively than ethanol, 1-propanol and urea, probably before producing an extensive conformation change.

Molecular mechanisms of dibromoalkane cytotoxicity in isolated rat hepatocytes.

Biochem. Pharmacol. 45(2) , 439-47, (1993)

The cytotoxicity of dibromoalkanes to isolated hepatocytes was proportional to the dibromoalkane concentration and increasing chain length of the dibromoalkane (C2-C6). The rapid hepatocyte glutathione (GSH) depletion which occurred upon addition of the dibro...