HI TOPK 032

HI TOPK 032 Structure
HI TOPK 032 structure
Common Name HI TOPK 032
CAS Number 487020-03-1 Molecular Weight 369.399
Density 1.5±0.1 g/cm3 Boiling Point 415.3±45.0 °C at 760 mmHg
Molecular Formula C20H11N5OS Melting Point N/A
MSDS Chinese USA Flash Point 204.9±28.7 °C
Symbol GHS07
GHS07
Signal Word Warning

PBK/TOPK mediates geranylgeranylation signaling for breast cancer cell proliferation.

Cancer Cell Int. 15 , 27, (2015)

PDZ binding-kinase (PBK) (also named T-lymphokine-activated killer cell-originated protein kinase (TOPK)), a serine/threonine kinase, is tightly controlled in normal tissues but elevated in many tumors, and functions in tumorigenesis and metastasis. However, ...