1,1-Dimethyl-4-phenylpiperazin-1-ium iodide
1,1-Dimethyl-4-phenylpiperazin-1-ium iodide structure
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Common Name | 1,1-Dimethyl-4-phenylpiperazin-1-ium iodide | ||
|---|---|---|---|---|
| CAS Number | 54-77-3 | Molecular Weight | 318.197 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C12H19IN2 | Melting Point | 234-238 °C(lit.) | |
| MSDS | USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Chemical genetics reveals a complex functional ground state of neural stem cells.
Nat. Chem. Biol. 3(5) , 268-273, (2007) The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain cancer. However, the complete repertoire of signaling pathways ... |
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Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Nat. Chem. Biol. 5 , 765-71, (2009) Studies of gene function and molecular mechanisms in Plasmodium falciparum are hampered by difficulties in characterizing and measuring phenotypic differences between individual parasites. We screened seven parasite lines for differences in responses to 1,279... |
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A potentially novel nicotinic receptor in Aplysia neuroendocrine cells.
J. Neurophysiol. 112(2) , 446-62, (2014) Nicotinic receptors form a diverse group of ligand-gated ionotropic receptors with roles in both synaptic transmission and the control of excitability. In the bag cell neurons of Aplysia, acetylcholine activates an ionotropic receptor, which passes inward cur... |
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Changes in Nicotinic Neurotransmission during Enteric Nervous System Development.
J. Neurosci. 35 , 7106-15, (2015) Acetylcholine-activating pentameric nicotinic receptors (nAChRs) are an essential mode of neurotransmission in the enteric nervous system (ENS). In this study, we examined the functional development of specific nAChR subtypes in myenteric neurons using Wnt1-C... |
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Luminal acetylcholine does not affect the activity of the CFTR in tracheal epithelia of pigs.
Int. Immunopharmacol. 29 , 166-72, (2015) Fluid homeostasis mediated by the airway epithelium is required for proper lung function, and the CFTR (cystic fibrosis transmembrane conductance regulator) Cl(-) channel is crucial for these processes. Luminal acetylcholine (ACh) acts as an auto-/paracrine m... |
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Facile construction of macroporous hybrid monoliths via thiol-methacrylate Michael addition click reaction for capillary liquid chromatography.
J. Chromatogr. A. , doi:10.1016/j.chroma.2014.12.031, (2014) A facile approach based on thiol-methacrylate Michael addition click reaction was developed for construction of porous hybrid monolithic materials. Three hybrid monoliths were prepared via thiol-methacrylate click polymerization by using methacrylate-polyhedr... |
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Effects of GPNMB on proliferation and odontoblastic differentiation of human dental pulp cells.
Int. J. Clin. Exp. Pathol. 8 , 6498-504, (2015) Glycoprotein (transmembrane) nonmetastatic melanoma protein b (GPNMB) plays crucial roles in odontogenesis. However, the role of GPNMB in human dental pulp cells (hDPCs) is still unclear. Therefore, in this study, we investigated the expression and function o... |
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Identification and mechanosensitivity of viscerofugal neurons.
Neuroscience 225 , 118-29, (2012) Enteric viscerofugal neurons are interneurons with cell bodies in the gut wall; they project to prevertebral ganglia where they provide excitatory synaptic drive to sympathetic neurons which control intestinal motility and secretion. Here, we studied the mech... |
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Early emergence of neural activity in the developing mouse enteric nervous system.
J. Neurosci. 31(43) , 15352-61, (2011) Neurons of the enteric nervous system (ENS) arise from neural crest cells that migrate into and along the developing gastrointestinal tract. A subpopulation of these neural-crest derived cells express pan-neuronal markers early in development, shortly after t... |
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Influence of polyphenolic compounds isolated from Rubus coreanum on catecholamine release in the rat adrenal medulla.
Arch. Pharm. Res. 30(10) , 1240-51, (2007) The aim of the present study was to investigate whether polyphenolic compounds isolated from wine brewed from Rubus coreanum MIQUEL (PCRC) may affect the release of catecholamine (CA) from the isolated perfused rat adrenal medulla, and to establish its mechan... |