Benazoline oxalate salt

Benazoline oxalate salt Structure
Benazoline oxalate salt structure
Common Name Benazoline oxalate salt
CAS Number 1021868-82-5 Molecular Weight 196.259003
Density N/A Boiling Point N/A
Molecular Formula C13H12N2•(C2H2O4) Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

Coupling of I(1) imidazoline receptors to the cAMP pathway: studies with a highly selective ligand, benazoline.

Mol. Pharmacol. 57 , 1142-51, (2000)

Clonidine and benazoline are two structurally related imidazolines. Whereas clonidine binds both to alpha(2)-adrenoceptors (alpha(2)R) and to I(1) imidazoline receptors (I(1)R), benazoline showed a high selectivity for imidazoline receptors. Although the alph...

Imidazoline receptors: qualitative structure-activity relationships and discovery of tracizoline and benazoline. Two ligands with high affinity and unprecedented selectivity.

Bioorg. Med. Chem. 5(5) , 833-841, (1997)

The observation that all the attempts to characterize imidazoline (I) receptors have been carried out with non-selective or poorly selective ligands prompted us to undertaken research aimed at developing selective ligand(s). In previous work using, as a start...