Methyl 3-nitrobenzoate
Methyl 3-nitrobenzoate structure
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Common Name | Methyl 3-nitrobenzoate | ||
|---|---|---|---|---|
| CAS Number | 618-95-1 | Molecular Weight | 181.145 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 284.7±13.0 °C at 760 mmHg | |
| Molecular Formula | C8H7NO4 | Melting Point | 78-80 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 136.8±21.8 °C | |
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Conformationally biased P3 amide replacements of beta-secretase inhibitors.
Bioorg. Med. Chem. Lett. 16(3) , 641-4, (2006) We have synthesized and evaluated a series of conformationally biased P3 amide replacements based on an isophthalamide lead structure. The studies resulted in the identification of the beta-secretase inhibitor 7m which has an in vitro IC(50)=35 nM. The synthe... |
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