Estra-1,3,5(10)-triene-3,16,17-triol,3-(hydrogen sulfate), sodium salt (1:1), (16a,17b)-

Estra-1,3,5(10)-triene-3,16,17-triol,3-(hydrogen sulfate), sodium salt (1:1), (16a,17b)- Structure
Estra-1,3,5(10)-triene-3,16,17-triol,3-(hydrogen sulfate), sodium salt (1:1), (16a,17b)- structure
Common Name Estra-1,3,5(10)-triene-3,16,17-triol,3-(hydrogen sulfate), sodium salt (1:1), (16a,17b)-
CAS Number 5150-64-1 Molecular Weight 390.42600
Density 1.432g/cm3 Boiling Point N/A
Molecular Formula C18H23NaO6S Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS08
GHS08
Signal Word Warning

Estriol and its conjugates in late pregnancy determined by extraction with Carbopack B and liquid chromatography with fluorometric detection.

Clin. Chem. 31(10) , 1698-702, (1985)

We report a method for measuring estriol and its intact conjugates in urine, serum, and amniotic fluid. A single assay can be done within about 50 min, eight samples assayed in less than 5 h. A 70-microL urine sample is diluted and the estriol conjugates are ...

Direct determination of estriol conjugates in amniotic fluid by capillary electrophoresis with electrospray tandem mass spectrometry.

Rapid Commun. Mass Spectrom. 20(19) , 2995-8, (2006)

Determination of estrogen 3-sulfates in biological fluids of mammary tumor-bearing rats by radioimmunoassay.

Nucl. Med. Biol. 20(4) , 493-501, (1993)

Determination of estradiol 3-sulfate (E2 3-S) and estriol 3-sulfate (E3 3-S) in plasma, urine or tumor tissues of mammary tumor-bearing rats were performed using the superior radioimmunoassay (RIA) system. The plasma level of E2 3-S after tumorigenesis was fo...

Bridge-heterologous chemiluminescence enzyme-linked immunosorbent assay of estriol 3-sulfate in pregnancy plasma.

Steroids 63(10) , 516-22, (1998)

A facile and sensitive chemiluminescence enzyme-linked immunosorbent assay (ELISA) of estriol 3-sulfate using a bridge-heterologous system was established. 6 alpha-Hydroxyestriol 3-sulfate 6-hemisuccinate was synthesized as a novel hapten. Antisera were raise...

Specific imaging of hormone-dependent mammary carcinoma in nude mice with [131I]-anti-estriol 3-sulfate antibody.

Nucl. Med. Biol. 22(5) , 547-53, (1995)

We tried to put the estrogen metabolite to use in tumor imaging. The antibody against estriol 3-sulfate (E3 3-S), which was one of the major metabolites of estrogen in hormone-dependent mammary carcinoma, was prepared and the tissue distribution and imaging o...

Esterase activity in human breast cyst fluid: associations with steroid sulfates and cations.

Steroids 57(10) , 485-7, (1992)

Human breast cyst fluid (BCF) contains an esterase that on the basis of electrophoretic mobility and response to inhibitors differs from those found in the plasma. From a total of 384 BCF samples analyzed for esterase using p-nitrophenyl hexanoate as substrat...

Specific antisera for the radioimmunoassay of estriol 3-sulfate.

Steroids 43(3) , 235-42, (1984)

Antisera were raised in male guinea pigs against 6-oxoestriol 3-sulfate O-carboxymethyloxime-bovine serum albumin (BSA) conjugate. The antisera to this antigen exhibited high affinity (Ka=4.7 X 10(9)M-1) and excellent specificity for estriol 3-sulfate, showin...

A simple radioimmunoassay for estriol 3-sulfate in pregnancy plasma without deconjugation.

Steroids 46(1) , 649-57, (1985)

A highly specific anti-estriol 3-sulfate antiserum was treated with 50% ammonium sulfate, and the crude globulin fraction was coupled to CNBr-activated Sepharose-4B. Addition of 0.1M Tris-HC1 buffer (pH 8.3) containing 0.1M glutamine to the solution of antige...

Prevention of co-elution of steroid sulfates with serum proteins from pre-column in column-switching HPLC system.

Biol. Pharm. Bull. 21(11) , 1211-4, (1998)

A method to prevent co-elution of steroid sulfates with proteins in serum from the pre-column in column-switching HPLC was developed. The pre-column, a polymer-coated mixed function column, was used for ion-pair chromatography with 5 mM tetra-n-butylammonium ...

Metabolism and biologic response of estrogen sulfates in hormone-dependent and hormone-independent mammary cancer cell lines. Effect of antiestrogens.

Ann. N. Y. Acad. Sci. 595 , 106-16, (1990)

Different estrogen-3-sulfates (estrone-3-sulfate, estradiol-3-sulfate, and estriol-3-sulfate) can provoke important biologic responses in different mammary cancer cell lines; there is a significant increase in progesterone receptor. However, no significant ef...