1-Azakenpaullone

1-Azakenpaullone Structure
1-Azakenpaullone structure
Common Name 1-Azakenpaullone
CAS Number 676596-65-9 Molecular Weight 328.163
Density 1.7±0.1 g/cm3 Boiling Point 648.8±50.0 °C at 760 mmHg
Molecular Formula C15H10BrN3O Melting Point >290ºC (dec.)
MSDS Chinese USA Flash Point 346.2±30.1 °C

Efficient definitive endoderm induction from mouse embryonic stem cell adherent cultures: a rapid screening model for differentiation studies.

Stem Cell Res. 12(1) , 166-77, (2014)

Definitive endoderm (DE) differentiation from mouse embryonic stem cell (mESC) monolayer cultures has been limited by poor cell survival or low efficiency. Recently, a combination of TGFβ and Wnt activation with BMP inhibition improved DE induction in embryoi...

WNT3 and membrane-associated β-catenin regulate trophectoderm lineage differentiation in human blastocysts.

Mol. Hum. Reprod. 21 , 711-22, (2015)

WNT/β-catenin signaling has been described as a crucial regulator of embryonic stem cells and embryogenesis. However, little is known on its role during human preimplantation embryo development, besides the RNA expression of its multiple players. In this stud...

GSK3β-dependent phosphorylation alters DNA binding, transactivity and half-life of the transcription factor USF2.

PLoS ONE 9(9) , e107914, (2014)

The upstream stimulatory factor 2 (USF2) is a regulator of important cellular processes and is supposed to have also a role during tumor development. However, the knowledge about the mechanisms that control the function of USF2 is limited. The data of the cur...