1-Azakenpaullone
1-Azakenpaullone structure
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Common Name | 1-Azakenpaullone | ||
|---|---|---|---|---|
| CAS Number | 676596-65-9 | Molecular Weight | 328.163 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 648.8±50.0 °C at 760 mmHg | |
| Molecular Formula | C15H10BrN3O | Melting Point | >290ºC (dec.) | |
| MSDS | Chinese USA | Flash Point | 346.2±30.1 °C | |
Use of 1-Azakenpaullone1-Azakenpaullone (1-Akp) is a highly selective and ATP-competitive inhibitor of glycogen synthase kinase-3 β (GSK-3β), with an IC50 value of 18 nM[1]. |
| Name | 1-Azakenpaullone |
|---|---|
| Synonym | More Synonyms |
| Description | 1-Azakenpaullone (1-Akp) is a highly selective and ATP-competitive inhibitor of glycogen synthase kinase-3 β (GSK-3β), with an IC50 value of 18 nM[1]. |
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| Related Catalog | |
| Target |
GSK-3β:18 nM (IC50) CDK1/cyclin B:2 μM (IC50) CDK5/p25:4.2 μM (IC50) |
| References |
| Density | 1.7±0.1 g/cm3 |
|---|---|
| Boiling Point | 648.8±50.0 °C at 760 mmHg |
| Melting Point | >290ºC (dec.) |
| Molecular Formula | C15H10BrN3O |
| Molecular Weight | 328.163 |
| Flash Point | 346.2±30.1 °C |
| Exact Mass | 327.000702 |
| PSA | 57.78000 |
| LogP | 3.19 |
| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
| Index of Refraction | 1.740 |
| Storage condition | -20°C Freezer |
| Water Solubility | DMSO: >10mg/mL |
| RIDADR | NONH for all modes of transport |
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| Pyrido[3',2':2,3]azepino[4,5-b]indol-6(5H)-one, 9-bromo-7,12-dihydro- |
| azakenpaullone |
| 9-Bromo-7,12-dihydropyrido[3',2':2,3]azepino[4,5-b]indol-6(5H)-one |
| 9-Bromo-7,12-dihydro-pyrido[3',2':2,3]azepino[4,5-b]indol-6(5H)-one |
| 1-Azakenpaullone |
| Kinome_3492 |
| HMS3229B07 |