Perfluorononanoic acid

Perfluorononanoic acid Structure
Perfluorononanoic acid structure
Common Name Perfluorononanoic acid
CAS Number 375-95-1 Molecular Weight 464.076
Density 1.8±0.1 g/cm3 Boiling Point 196.4±35.0 °C at 760 mmHg
Molecular Formula C9HF17O2 Melting Point 59-62 °C(lit.)
MSDS Chinese USA Flash Point 72.6±25.9 °C
Symbol GHS07
GHS07
Signal Word Warning

Sources and fate of perfluorinated compounds in the aqueous environment and in drinking water of a highly urbanized and industrialized area in Italy.

J. Hazard. Mater. 282 , 51-60, (2014)

Perfluorinated substances are listed among emerging contaminants because they are globally distributed, environmentally persistent, bioaccumulative and potentially harmful. In a three-year monitoring campaign (2010-2013) we investigated the occurrence, source...

Determination of perfluorinated alkyl acids in corn, popcorn and popcorn bags before and after cooking by focused ultrasound solid-liquid extraction, liquid chromatography and quadrupole-time of flight mass spectrometry.

J. Chromatogr. A. 1355 , 211-8, (2014)

An analytical method is proposed to determine ten perfluorinated alkyl acids (PFAAs) [nine perfluorocarboxylic acids (PFCAs) and perfluorooctane sulfonate (PFOS)] in corn, popcorn and microwave popcorn packaging by focused ultrasound solid-liquid extraction (...

Chemometric strategy for untargeted lipidomics: biomarker detection and identification in stressed human placental cells.

Anal. Chim. Acta 854 , 20-33, (2014)

A lipidomic study was developed in a human placental choriocarcinoma cell line (JEG-3) exposed to tributyltin (TBT) and to a mixture of perfluorinated chemicals (PFCs). The method was based on the application of multivariate curve resolution-alternating least...

Development of an analytical method for the targeted screening and multi-residue quantification of environmental contaminants in urine by liquid chromatography coupled to high resolution mass spectrometry for evaluation of human exposures.

Talanta 146 , 694-706, (2015)

The aim of this study was to develop an analytical method and contribute to the assessment of the Exposome. Thus, a targeted analysis of a wide range of contaminants in contact with humans on daily routines in urine was developed. The method focused on a list...

Microminipigs as a new experimental animal model for toxicological studies: comparative pharmacokinetics of perfluoroalkyl acids.

J. Appl. Toxicol. 36 , 68-75, (2015)

In this study, we evaluated the efficacy of a novel minipig strain, the Microminipig (MMPig), as an animal model for studying the pharmacokinetics of a mixture of 10 perfluoroalkyl acids (PFAAs). After a single oral dose was given, we found that the blood dep...

Online background cleanup followed by high-performance liquid chromatography with tandem mass spectrometry for the analysis of perfluorinated compounds in human blood.

J. Sep. Sci. 38(2) , 247-53, (2015)

In this study, a novel method for the analysis of perfluorinated compounds in whole blood has been developed and validated. The method was developed by using a conventional reversed-phase C18 column as a trapping column for the elimination of background conta...

Environmental contaminants activate human and polar bear (Ursus maritimus) pregnane X receptors (PXR, NR1I2) differently.

Toxicol. Appl. Pharmacol. 284(1) , 54-64, (2015)

Many persistent organic pollutants (POPs) accumulate readily in polar bears because of their position as apex predators in Arctic food webs. The pregnane X receptor (PXR, formally NR1I2, here proposed to be named promiscuous xenobiotic receptor) is a xenobiot...

Characterization of complex lipid mixtures in contaminant exposed JEG-3 cells using liquid chromatography and high-resolution mass spectrometry.

Environ. Sci. Pollut. Res. Int. 21(20) , 11907-16, (2014)

The aim of this study was to develop a method based on ultra high performance liquid chromatography coupled with mass spectrometry (UHPLC-MS) for lipid profiling in human placental choriocarcinoma (JEG-3) cells. Lipids were solid-liquid extracted from JEG-3 c...

Spatiotemporal distribution and mass loadings of perfluoroalkyl substances in the Yangtze River of China.

Sci. Total Environ. 493 , 580-7, (2014)

A systematic investigation into contamination profiles of eighteen perfluoroalkyl substances (PFASs) in both surface water and sediments of Yangtze River was carried out by using high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) in ...

Reversible and irreversible sorption of perfluorinated compounds (PFCs) by sediments of an urban reservoir.

Chemosphere 144 , 1747-53, (2015)

Uncertainty about the extent to which contaminant sorption by suspended solids and bed sediments is irreversible is a major impediment for modeling and managing the water quality of surface water resources. This study examined reversible and irreversible sorp...