4-Chlorophenyl Chloroformate

4-Chlorophenyl Chloroformate Structure
4-Chlorophenyl Chloroformate structure
Common Name 4-Chlorophenyl Chloroformate
CAS Number 7693-45-0 Molecular Weight 191.012
Density 1.4±0.1 g/cm3 Boiling Point 222.6±13.0 °C at 760 mmHg
Molecular Formula C7H4Cl2O2 Melting Point N/A
MSDS Chinese USA Flash Point 103.3±0.0 °C
Symbol GHS05 GHS06
GHS05, GHS06
Signal Word Danger

Inhibition of glyoxalase I by the enediol mimic S-(N-hydroxy-N-methylcarbamoyl)glutathione. The possible basis of a tumor-selective anticancer strategy.

J. Biol. Chem. 267(35) , 24933-6, (1992)

In principle, competitive inhibitors of glyoxalase I that also serve as substrates for the thioester hydrolase glyoxalase II might function as tumor-selective anti-cancer agents, given the role of these enzymes in removing cytotoxic methylglyoxal from cells a...