triphenylsilanamine

triphenylsilanamine Structure
triphenylsilanamine structure
Common Name triphenylsilanamine
CAS Number 4215-80-9 Molecular Weight 275.420
Density 1.1±0.1 g/cm3 Boiling Point 366.5±15.0 °C at 760 mmHg
Molecular Formula C18H17NSi Melting Point 60-62ºC(lit.)
MSDS Chinese USA Flash Point 175.5±20.4 °C
Symbol GHS07
GHS07
Signal Word Warning

High-throughput HPLC-MS/MS determination of the persistence of neonicotinoid insecticide residues of regulatory interest in dietary bee pollen.

Anal. Bioanal. Chem 407 , 7101-10, (2015)

The aim of this work is the development of a simple, fast, quantitative, and economic method for the determination of neonicotinoid insecticide residues in dietary bee pollen. Several parameters of the method, such as extraction solvent, extraction time, and ...

Cyclic-RGDfK peptide conjugated succinoyl-TPGS nanomicelles for targeted delivery of docetaxel to integrin receptor over-expressing angiogenic tumours.

Nanomedicine: Nanotechnology, Biology, and Medicine 11 , 1511-20, (2015)

Docetaxel (DTX) is an anticancer drug that is used alone and in combination with other drugs to treat tumours. However, it suffers from the drawback of non-specific cytotoxicity. To improve the therapeutic potential of DTX, we report the synthesis of cRGDfK p...

CNS drug design: balancing physicochemical properties for optimal brain exposure.

J. Med. Chem. 58(6) , 2584-608, (2015)

The human brain is a uniquely complex organ, which has evolved a sophisticated protection system to prevent injury from external insults and toxins. Designing molecules that can overcome this protection system and achieve optimal concentration at the desired ...

Approaches for the coating of capillary columns with highly phenylated stationary phases for high-temperature GC.

J. Sep. Sci. 27(4) , 335-42, (2004)

Two highly phenylated tetramethyl-p-silphenylene-diphenylsiloxane copolymers were coated on fused silica capillary columns and used as stationary phases in GC. The copolymers offered new insights into the coating process and column preparation due to their ph...

Novel aspects of the transamination reaction between Ti(NMe2)4 and primary amines.

Dalton Trans. 42(34) , 12203-19, (2013)

A detailed study of the transamination reaction between Ti(NMe2)4 and primary amines RNH2 is reported Alkylamines (1-adamantylamine, t-butylamine) and triphenylsilylamine yield dimers of the type [Ti(μ-NR)(NMe2)2]2 (R = 1-adamantyl (1), (t)Bu (2), SiPh3 (3))....

More effective DPP4 inhibitors as antidiabetics based on sitagliptin applied QSAR and clinical methods.

Curr. Comput. Aided. Drug Des. 10(3) , 237-49, (2015)

Xanthine-based molecules such as serine protease dipeptidyl peptidase 4 (DPP4) inhibitors are compounds often used in improving glycemic control in type 2 diabetic patients and also used for their effects as mild stimulants and as bronchodilators, notably in ...

Molecular modeling, synthesis and biological evaluation of N-heteroaryl compounds as reverse transcriptase inhibitors against HIV-1.

Chem. Biol. Drug Des. 85(3) , 336-47, (2015)

Different N-heteroaryl compounds bearing pyrimidine and benzimidazole moieties have been designed in silico using Discovery studio 2.5 software, synthesized and evaluated for their inhibitory activity as reverse transcriptase inhibitors against HIV-1 replicat...

Synthesis and reactions of some new organometallic compounds: synthesis of triphenylsilylsulfinylamine. Ahmed GA, et al.

Phosph. Sulfur Relat. Elem. 69(3-4) , 253-255, (1992)

Study on Mo/HZSM-5 catalysts modified by bulky aminoalkyl-substituted silyl compounds for the selective methane-to-benzene (MTB) reaction. Kikuchi S, et al.

J. Catal. 242(2) , 349-56, (2006)

Selective palladium-catalyzed amination of the heterocyclic core of variolins. Baeza A, et al.

Tetrahedron Lett. 48(14) , 2597-2601., (2007)