acemetacin
acemetacin structure
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Common Name | acemetacin | ||
|---|---|---|---|---|
| CAS Number | 53164-05-9 | Molecular Weight | 415.824 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 565.5±50.0 °C at 760 mmHg | |
| Molecular Formula | C21H18ClNO6 | Melting Point | 151.5°C | |
| MSDS | Chinese USA | Flash Point | 295.8±30.1 °C | |
| Symbol |
GHS06 |
Signal Word | Danger | |
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A comparison of low-molecular-weight heparin and combined therapy of low-molecular-weight heparin with an anti-inflammatory agent in the treatment of superficial vein thrombosis.
Phlebology 24(2) , 56-60, (2009) The optimal treatment of superficial vein thrombosis (SVT) of the leg has not been determined yet. The aim of this study is to evaluate the efficacy of low-molecular-weight heparin (LMWH) as compared with combined therapy of LMWH with an anti-inflammatory age... |
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A fast and reliable spectroscopic method for the determination of membrane--water partition coefficients of organic compounds.
Lipids 36(1) , 89-96, (2001) Partition coefficients (Kp) between egg yolk phosphatidylcholine multilamellar vesicles and water were determined for two nonsteroidal anti-inflammatory drugs (indomethacin and acemetacin) using two independent methodologies: derivative spectrophotometry and ... |
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Multivariate optimization of separation conditions for simultaneous determination of acemetacin and chlorzoxazone in a pharmaceutical preparation by HPLC using response surface methodology.
J. AOAC Int. 96(4) , 723-9, (2013) A new, fast, accurate, precise, and sensitive RP-HPLC method for the simultaneous determination of acemetacin and chlorzoxazone has been developed. Response surface methodology with a central composite design was used to optimize the acetonitrile and ammonium... |
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Pharmacokinetics of acemetacin and its active metabolite indomethacin in rats during acute hepatic damage and liver regeneration.
Ann. Hepatol. 8(2) , 141-7, (2009) The pharmacokinetics of acemetacin, a non-steroidal anti-inflammatory drug which is biotransformed to indomethacin by hepatic first-pass effect, was examined during the necrotic and regeneration phases resulting from acute hepatitis induced by carbon tetrachl... |
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[Treatment of osteoarthritis of the knee joint. Efficacy and tolerance to acemetacin slow release in comparison to celecoxib].
Orthopade. 33(9) , 1032-41, (2004) The aim of this trial was to compare acemetacin (ACE) with celecoxib (CEL) in terms of tolerability and efficacy in the treatment of osteoarthritis of the knee joint.A total of 105 patients (26-64 years old) suffering from primary osteoarthritis (OA) of the k... |
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Bartter's Syndrome with Type 2 Diabetes Mellitus
J. Chin. Med. Assoc. 72(2) , 88-90, (2009) We report a rare case of Bartter's syndrome in a 35-year-old woman with type 2 diabetes mellitus. The patient presented with leg weakness, fatigue, polyuria and polydipsia. Hypokalemia, metabolic alkalosis, and high renin and aldosterone concentrations were p... |
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[The hydroxam reaction of indometacin and acemetacin].
Pharmazie 58(6) , 431-2, (2003)
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Lack of influence of body mass index on efficacy and tolerance of acemetacin in short-term treatment of musculoskeletal diseases.
Rheumatol. Int. 27(4) , 351-5, (2007) Dose adjustments of NSAIDs according to body weight may be reasonable for an optimal efficacy/tolerance profile in the therapy of musculoskeletal disorders, but are unusual in adults. In this post hoc analysis of a prospective, one-arm clinical study of a sho... |
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[Clinical profile of acemetacin].
Med. Klin. (Munich.) 85(5) , 340-6, 352, (1990)
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Late drug eluting stent thrombosis due to acemetacine: type III Kounis syndrome: Kounis syndrome due to acemetacine.
Int. J. Cardiol. 155(3) , 461-2, (2012)
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