1,4-Dithiane-2,5-diol

1,4-Dithiane-2,5-diol Structure
1,4-Dithiane-2,5-diol structure
Common Name 1,4-Dithiane-2,5-diol
CAS Number 40018-26-6 Molecular Weight 152.235
Density 1.5±0.1 g/cm3 Boiling Point 360.9±42.0 °C at 760 mmHg
Molecular Formula C4H8O2S2 Melting Point 130 °C (dec.)(lit.)
MSDS Chinese USA Flash Point 175.5±26.6 °C
Symbol GHS05 GHS06
GHS05, GHS06
Signal Word Danger

Effect of lipid composition on meat-like model systems containing cysteine, ribose, and polyunsaturated fatty acids.

J. Agric. Food Chem. 50(5) , 1126-32, (2002)

This paper compares the volatile constituents of model systems containing the important meat aroma precursors cysteine and ribose, with and without either methyl linoleate, an n-6 fatty acid, or methyl alpha-linolenate, an n-3 acid, both of which are present ...

Phytogrowth-inhibitory and antibacterial activities of 2,5-dihydroxy-1,4-dithiane and its derivatives.

Chem. Pharm. Bull. 38(1) , 243-5, (1990)

2,5-Dihydroxy-1,4-dithiane (I) and its derivatives (II-IV) showed rather marked inhibitory activities on the growth of the roots of two plant species. All compounds tested had phytogrowth-inhibitory activities. These compounds markedly inhibited the growth of...

Synthesis and antiviral/antitumor evaluation of 2-amino- and 2-carboxamido-3-arylsulfonylthiophenes and related compounds as a new class of diarylsulfones.

Bioorg. Med. Chem. 9(5) , 1123-32, (2001)

Based on general SARs previously described for anti-HIV-1 diarylsulfone derivatives, a series of 2-amino- and 2-carboxamido-3-arylsulfonylthiophenes has been prepared and evaluated as potential antiviral and antitumor agents. In cell culture, some of the 2-am...

Hydrogen-bond-mediated cascade reaction involving chalcones: facile synthesis of enantioenriched trisubstituted tetrahydrothiophenes.

Org. Lett. 14(4) , 1090-3, (2012)

A bifunctional squaramide catalyzed sulfa-Michael/aldol cascade reaction between 1,4-dithiane-2,5-diol and chalcones with a low catalyst loading has been developed. Trisubstituted tetrahydrothiophenes with three contiguous stereogenic centers are obtained in ...

Highly diastereoselective DABCO-catalyzed [3 + 3]-cycloaddition of 1,4-dithiane-2,5-diol with azomethine imines.

Org. Lett. 15(21) , 5554-7, (2013)

An effective diastereoselective [3 + 3] cycloaddition of 1,4-dithiane-2,5-diol with azomethine imines catalyzed by DABCO is described. A variety of highly functionalized six-membered dinitrogen-fused heterocycles can be obtained in good yield with excellent d...

1, 4-Dithiane-2, 5-diol as an efficient synthon for a straightforward synthesis of functionalized tetrahydrothiophenes via sulfa-Michael/aldol-type reactions with electrophilic alkenes. Baricordi N, et al.

Tetrahedron 68(1) , 208-213, (2012)

Convenient 'one-pot'synthesis of 3, 4-substituted tetrahydrothiophenes through tandem Michael-Henry and Michael-Michael reactions. Barco A, et al.

Tetrahedron Lett. 47(46) , 8087-8090, (2006)