Cyclopentylamine
Cyclopentylamine structure
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Common Name | Cyclopentylamine | ||
|---|---|---|---|---|
| CAS Number | 1003-03-8 | Molecular Weight | 85.147 | |
| Density | 0.9±0.1 g/cm3 | Boiling Point | 110.0±8.0 °C at 760 mmHg | |
| Molecular Formula | C5H11N | Melting Point | -85°C | |
| MSDS | Chinese USA | Flash Point | 17.2±0.0 °C | |
| Symbol |
GHS02, GHS05, GHS06 |
Signal Word | Danger | |
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Structure-kinetic relationships--an overlooked parameter in hit-to-lead optimization: a case of cyclopentylamines as chemokine receptor 2 antagonists.
J. Med. Chem. 56(19) , 7706-14, (2013) Preclinical models of inflammatory diseases (e.g., neuropathic pain, rheumatoid arthritis, and multiple sclerosis) have pointed to a critical role of the chemokine receptor 2 (CCR2) and chemokine ligand 2 (CCL2). However, one of the biggest problems of high-a... |
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Cytostatic and antitumour properties of a new series of Pt (II) complexes with cyclopentylamine.
In Vivo 1(4) , 229-34, (1987) Ten new Pt (II) complexes were synthesized and tested as potential antitumor drugs in vitro on KB human tumour cell line, and in vivo against four experimental tumour systems (P388, L1210, ADJ/PC6A and Yoshida sarcoma). The complexes contained two primary ami... |
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Influenza virus M2 protein: a molecular modelling study of the ion channel.
Protein Eng. 6(1) , 65-74, (1993) The influenza A M2 protein forms cation-selective ion channels which are blocked by the anti-influenza drug amantadine. A molecular model of the M2 channel is presented in which a bundle of four parallel M2 transbilayer helices surrounds a central ion-permeab... |
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Synthesis of C-5'-nor-dideoxycarbanucleosides structurally related to neplanocin C.
Nucleosides Nucleotides 18(10) , 2219-31, (1999) Purine carbanucleosides built on a 6-oxabicyclo[3.1.0]hexane template were synthesized from readily available 2-cyclopentenone employing a Mitsunobu reaction to incorporate the base onto the carbocyclic ring. Both adenosine and guanosine analogues exhibited m... |