Tyrphostin AG 1112
Tyrphostin AG 1112 structure
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Common Name | Tyrphostin AG 1112 | ||
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| CAS Number | 153150-84-6 | Molecular Weight | 274.28 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C15H10N6 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
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Protein kinase inhibitors as a therapeutic modality.
Acc. Chem. Res. 36(6) , 462-9, (2003) Most of the signal transduction pathways are mediated by protein kinases regulating every aspect of cell function. Mutations which deregulate their expression or their function or both result in cancers. Therefore, protein kinase inhibitors has become the foc... |
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Tyrphostin-induced inhibition of p210bcr-abl tyrosine kinase activity induces K562 to differentiate.
Blood 82(12) , 3524-9, (1993) We report on the potency of two Tyrphostin tyrosine kinase blockers, AG 1112 and AG 568, to inhibit p210bcr-abl tyrosine kinase activity in K562 cells, concomitant with the induction of erythroid differentiation. AG 568 and especially AG 1112 represent a spec... |
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