DC Chemicals Limited
China
Product Name: Tyrphostin AG 1112
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: TYRPHOSTIN AG 1112
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

153150-84-6

153150-84-6 structure

153150-84-6 structure

Name: Tyrphostin AG 1112
Chemical Name: TYRPHOSTIN AG 1112
CAS Number: 153150-84-6
Molecular Formula: C₁₅H₁₀N₆
Molecular Weight: 274.28
Create Date: 2018-07-07 10:20:49
Modify Date: 2024-01-12 19:22:37
Tyrphostin AG1112 is a potent inhibitors of CK II. Tyrphostin AG1112 inhibits p210bcr-abl tyrosine kinase, with IC50 values of 2, 15, 20 μM in p210bcr-abl, EGFR and PDGFR cells, respectively[1][2].

Name	TYRPHOSTIN AG 1112

Description	Tyrphostin AG1112 is a potent inhibitors of CK II. Tyrphostin AG1112 inhibits p210bcr-abl tyrosine kinase, with IC50 values of 2, 15, 20 μM in p210bcr-abl, EGFR and PDGFR cells, respectively[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Tyrosinase Signaling Pathways >> Cell Cycle/DNA Damage >> Casein Kinase Signaling Pathways >> Stem Cell/Wnt >> Casein Kinase
In Vitro	Tyrphostin AG1112 (0-100 μM) dose-dependently induces differentiation also induce specific growth arrest[1].
References	[1]. T B Kang, et al. Action of 3 tyrphostin derivatives on casein kinase II from rat liver. Zhongguo Yao Li Xue Bao. 1997 Jan;18(1):56-8. [2]. M Anafi, et al. Tyrphostin-induced inhibition of p210bcr-abl tyrosine kinase activity induces K562 to differentiate. Blood. 1993 Dec 15;82(12):3524-9.

Molecular Formula	C₁₅H₁₀N₆
Molecular Weight	274.28
Appearance	solid
Storage condition	−20°C

Hazard Codes	Xn
Risk Phrases	36/37/38-40
Safety Phrases	26-36/37
RIDADR	NONH for all modes of transport
WGK Germany	1