ICSH
ICSH structure
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Common Name | ICSH | ||
|---|---|---|---|---|
| CAS Number | 9002-67-9 | Molecular Weight | N/A | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | N/A | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS08 |
Signal Word | Danger | |
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Interactions between kisspeptins and neurokinin B.
Adv. Exp. Med. Biol. 784 , 325-47, (2013) Reproductive function is tightly regulated by an intricate network of central and peripheral factors; however, the precise mechanism triggering critical reproductive events, such as puberty onset, remains largely unknown. Recently, the neuropeptides kisspepti... |
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Neurokinin B signaling in the female rat: a novel link between stress and reproduction.
Endocrinology 155(7) , 2589-601, (2014) Acute systemic stress disrupts reproductive function by inhibiting pulsatile gonadotropin secretion. The underlying mechanism involves stress-induced suppression of the GnRH pulse generator, the functional unit of which is considered to be the hypothalamic ar... |
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Electrophysiology of arcuate neurokinin B neurons in female Tac2-EGFP transgenic mice.
Endocrinology 155(7) , 2555-65, (2014) Neurons in the arcuate nucleus that coexpress kisspeptin, neurokinin B (NKB), and dynorphin (KNDy neurons) play an important role in the modulation of reproduction by estrogens. Here, we study the anatomical and electrophysiological properties of arcuate NKB ... |
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The kisspeptin-GnRH pathway in human reproductive health and disease.
Hum. Reprod. Update 20(4) , 485-500, (2014) The discovery of kisspeptin as key central regulator of GnRH secretion has led to a new level of understanding of the neuroendocrine regulation of human reproduction. The related discovery of the kisspeptin-neurokinin B-dynorphin (KNDy) pathway in the last de... |
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Insulin-like growth factor-I regulates LH release by modulation of kisspeptin and NMDA-mediated neurotransmission in young and middle-aged female rats.
Endocrinology 155(5) , 1827-37, (2014) This study investigated potential mechanisms by which age and IGF-I receptor (IGF-Ir) signaling in the neuroendocrine hypothalamus affect estradiol-positive feedback effects on GnRH neuronal activation and on kisspeptin and N-methyl-D-aspartate (NMDA)-induced... |
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Anogenital distance plasticity in adulthood: implications for its use as a biomarker of fetal androgen action.
Endocrinology 156(1) , 24-31, (2015) Androgen action during the fetal masculinization programming window (MPW) determines the maximum potential for growth of androgen-dependent organs (eg, seminal vesicles, prostate, penis, and perineum) and is reflected in anogenital distance (AGD). As such, de... |
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Regulatory Role of Gonadotropins and Local Factors Produced by Ovarian Follicles on In Vitro Resistin Expression and Action on Porcine Follicular Steroidogenesis.
Biol. Reprod. 92 , 142, (2015) Resistin, a hormone secreted by adipocytes, is thought to be important in reproduction. Our previous study demonstrated resistin expression in porcine ovarian follicles and its direct effect on steroidogenesis. The aim of the current study was to evaluate the... |
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Longer anogenital distance is associated with higher testosterone levels in women: a cross-sectional study.
BJOG 121(11) , 1359-64, (2014) Animal models have suggested that anogenital distance (AGD) at birth reflects androgen levels during in utero development and predicts adult AGD. A recent study showed an association between perineal length and androgen levels in men, suggesting that serum te... |
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Kisspeptin cell-specific PI3K signaling regulates hypothalamic kisspeptin expression and participates in the regulation of female fertility.
Am. J. Physiol. Endocrinol. Metab. 307(11) , E969-82, (2014) Hypothalamic kisspeptin neurons integrate and translate cues from the internal and external environments that regulate gonadotropin-releasing hormone (GnRH) secretion and maintain fertility in mammals. However, the intracellular signaling pathways utilized to... |
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[Specifics of hormonal and energy balance in patients with hyperplasia and endometrial neoplasia with metabolic syndrome in the background].
Vopr. Onkol. 59(1) , 65-71, (2013) We conducted a comparative investigation of the hormonal status (LH, FSH, estradiol, progesterone, testosterone, prolactin, SHBG), energy status (leptin, ghrelin, insulin), and carbohydrate and lipid metabolism in patients with endometrial hyperplasia and neo... |