Heptamethyleneimine

Heptamethyleneimine Structure
Heptamethyleneimine structure
Common Name Heptamethyleneimine
CAS Number 1121-92-2 Molecular Weight 113.20100
Density 0.951 g/mL at 25 °C(lit.) Boiling Point 51-53 °C15 mm Hg(lit.)
Molecular Formula C7H15N Melting Point 17-19 °C(lit.)
MSDS Chinese USA Flash Point 85 °F
Symbol GHS02 GHS05
GHS02, GHS05
Signal Word Danger

Anti-cancer fatty-acid derivative induces autophagic cell death through modulation of PKM isoform expression profile mediated by bcr-abl in chronic myeloid leukemia.

Cancer Lett. 360(1) , 28-38, (2015)

The fusion gene bcr-abl develops chronic myeloid leukemia (CML), and stimulates PI3K/Akt/mTOR signaling, leading to impaired autophagy. PI3K/Akt/mTOR signaling also plays an important role in cell metabolism. The Warburg effect is a well-recognized hallmark o...