DIEA
DIEA structure
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Common Name | DIEA | ||
|---|---|---|---|---|
| CAS Number | 7087-68-5 | Molecular Weight | 129.243 | |
| Density | 0.8±0.1 g/cm3 | Boiling Point | 126.5±0.0 °C at 760 mmHg | |
| Molecular Formula | C8H19N | Melting Point | -46 °C | |
| MSDS | Chinese USA | Flash Point | 10.6±0.0 °C | |
| Symbol |
GHS02, GHS05, GHS06 |
Signal Word | Danger | |
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Formulation of highly functionalizable DNA nanoparticles based on 1,2-dithiolane derivatives.
ChemBioChem. 16(5) , 792-804, (2015) We describe the formulation of synthetic virus models based on ionic compounds bearing the polymerizable 1,2-dithiolane moiety. First, cationic amphiphiles containing the polymeric inducer were prepared and used to efficiently condense a DNA plasmid (pDNA) in... |
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Covalent and stable CuAAC modification of silicon surfaces for control of cell adhesion.
ChemBioChem. 16(5) , 782-91, (2015) Stable primary functionalization of metal surfaces plays a significant role in reliable secondary attachment of complex functional molecules used for the interfacing of metal objects and nanomaterials with biological systems. In principle, this can be achieve... |
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Quantification of plasma HIV RNA using chemically engineered peptide nucleic acids.
Nat. Commun. 5 , 5079, (2014) The remarkable stability of peptide nucleic acids (PNAs) towards enzymatic degradation makes this class of molecules ideal to develop as part of a diagnostic device. Here we report the development of chemically engineered PNAs for the quantitative detection o... |
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A cell-ECM screening method to predict breast cancer metastasis.
Integr. Biol. (Camb.) 7(2) , 198-212, (2015) Breast cancer preferentially spreads to the bone, brain, liver, and lung. The clinical patterns of this tissue-specific spread (tropism) cannot be explained by blood flow alone, yet our understanding of what mediates tropism to these physically and chemically... |
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Antisense Oligonucleotide-mediated Suppression of Muscle Glycogen Synthase 1 Synthesis as an Approach for Substrate Reduction Therapy of Pompe Disease.
Mol. Ther. Nucleic Acids 3 , e206, (2014) Pompe disease is an autosomal recessive disorder caused by a deficiency of acid α-glucosidase (GAA; EC 3.2.1.20) and the resultant progressive lysosomal accumulation of glycogen in skeletal and cardiac muscles. Enzyme replacement therapy using recombinant hum... |
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Antimicrobial properties of membrane-active dodecapeptides derived from MSI-78.
Biochim. Biophys. Acta 1848(5) , 1139-46, (2015) Antimicrobial peptides (AMPs) are a class of broad-spectrum antibiotics known by their ability to disrupt bacterial membranes and their low tendency to induce bacterial resistance, arising as excellent candidates to fight bacterial infections. In this study w... |
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Diels-Alder hydrogels with enhanced stability: First step toward controlled release of bevacizumab.
Eur. J. Pharm. Biopharm. 96 , 217-25, (2015) Eight-armed PEG was functionalized with furyl and maleimide groups (8armPEG20k-Fur and 8armPEG20k-Mal); degradable hydrogels were obtained by cross-linking via Diels-Alder chemistry. To increase the stability to degradation, the macromonomers were modified by... |
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Design and characterization of ebolavirus GP prehairpin intermediate mimics as drug targets.
Protein Sci. 24(4) , 446-63, (2015) Ebolaviruses are highly lethal filoviruses that cause hemorrhagic fever in humans and nonhuman primates. With no approved treatments or preventatives, the development of an anti-ebolavirus therapy to protect against natural infections and potential weaponizat... |
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The influence of linker length on the properties of cathepsin S cleavable177Lu-labeled HPMA copolymers for pancreatic cancer imaging
Biomaterials 35(22) , 5760-70, (2014) N-(2-hydroxypropyl)-methacrylamide (HPMA) copolymers have shown promise for application in the detection and staging of cancer. However, non-target accumulation, particularly in the liver and spleen, hinders the detection of resident or nearby metastatic lesi... |
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Sensitive naked eye detection of hydrogen sulfide and nitric oxide by aza-BODIPY dyes in aqueous medium.
Anal. Chem. 86(18) , 9335-42, (2014) With an objective to develop optical probes for biologically important anions and neutral molecules, we synthesized three novel NIR absorbing aza-BODIPY derivatives, 3a-3c, and have systematically tuned their photophysical properties by changing the periphera... |