pTH-Related Protein (1-40) (human, mouse, rat) trifluoroacetate salt
pTH-Related Protein (1-40) (human, mouse, rat) trifluoroacetate salt structure
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Common Name | pTH-Related Protein (1-40) (human, mouse, rat) trifluoroacetate salt | ||
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| CAS Number | 120298-73-9 | Molecular Weight | N/A | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C207H334N66O58 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
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Parathyroid hormone-related peptide stimulates proliferation of highly tumorigenic human SV40-immortalized breast epithelial cells.
J. Bone Miner Res. 15 , 2129-2139, (2000) Parathyroid hormone-related protein (PTHrP) is the main mediator of humoral hypercalcemia of malignancy (HHM) and it is produced by many tumors, including breast cancers. Breast epithelial cells as well as breast cancer tumors and cell lines have been reporte... |
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Tumor necrosis factor enhances parathyroid hormone-related protein-induced hypercalcemia and bone resorption without inhibiting bone formation in vivo.
Cancer Res. 57 , 3194-3199, (1997) Humoral hypercalcemia of malignancy results from the effects of tumor-produced factors on bone, kidney, and intestine that disrupt normal calcium homeostasis. Although parathyroid hormone-related protein (PTHrP) is a major mediator of the syndrome, tumors als... |
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Effects of transforming growth factor-alpha on parathyroid hormone- and parathyroid hormone-related protein-mediated bone resorption and adenylate cyclase stimulation in vitro.
Domest. Anim. Endocrinol. 8 , 499-507, (1991) The effects of transforming growth factor-alpha (TGF alpha) were determined on the ability of parathyroid hormone (PTH) or parathyroid hormone-related protein (PTHrP) to stimulate bone resorption and adenylate cyclase in vitro. Bovine PTH-(1-34) and human PTH... |
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Characterization of parathyroid hormone/parathyroid hormone-related protein receptor and signaling in hypercalcemic Walker 256 tumor cells.
J. Endocrinol. 166 , 11-20, (2000) Parathyroid hormone (PTH)-related protein (PTHrP) is the main factor responsible for humoral hypercalcemia of malignancy. Both PTH and PTHrP bind to the common type I PTH/PTHrP receptor (PTHR), thereby activating phospholipase C and adenylate cyclase through ... |
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A parathyroid hormone-related protein implicated in malignant hypercalcemia: cloning and expression.
Science 237 , 893, (1987) Humoral hypercalcemia of malignancy is a common complication of lung and certain other cancers. The hypercalcemia results from the actions of tumor factors on bone and kidney. We report here the isolation of full-length complementary DNA clones of a putative ... |
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Parathyroid hormone-related protein purified from a human lung cancer cell line.
Proc. Natl. Acad. Sci. U. S. A. 84 , 5048, (1987) A protein with biological activities similar to parathyroid hormone (PTH) has been purified from serum-free culture medium obtained from a human lung cancer cell line (BEN). A major protein band of 18 kDa was obtained on NaDodSO4/polyacrylamide gels, with fai... |
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Parathyroid hormone-related peptide and primary hyperparathyroidism. Testini M, Gurrado A, et al.
Front. Biosci. 2 , 299-312, (2010)
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