ω-Agatoxin IVa trifluoroacetate salt
ω-Agatoxin IVa trifluoroacetate salt structure
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Common Name | ω-Agatoxin IVa trifluoroacetate salt | ||
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| CAS Number | 145017-83-0 | Molecular Weight | N/A | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C217H360N68O60S10 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
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P-type calcium channels blocked by the spider toxin omega-Aga-IVA.
Nature 355 , 827-829, (1992) Voltage-dependent calcium channels mediate calcium entry into neurons, which is crucial for many processes in the brain including synaptic transmission, dendritic spiking, gene expression and cell death. Many types of calcium channels exist in mammalian brain... |
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P-type calcium channels in rat central and peripheral neurons.
Neuron 9 , 85-95, (1992) The peptide toxin omega-Aga-IVA blocked P-type Ca2+ channel current in rat Purkinje neurons (KD approximately 2 nM) but had no effect on identified T-type, L-type, or N-type currents in a variety of central and peripheral neurons. omega-Aga-IVA blocked a subs... |
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Calcium channels coupled to glutamate release identified by omega-Aga-IVA.
Science 258 , 310-313, (1992) Presynaptic calcium channels are crucial elements of neuronal excitation-secretion coupling. In mammalian brain, they have been difficult to characterize because most presynaptic terminals are too small to probe with electrodes, and available pharmacological ... |