NPS-2143 hydrochloride
NPS-2143 hydrochloride structure
|
Common Name | NPS-2143 hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 324523-20-8 | Molecular Weight | 445.381 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H26Cl2N2O2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07, GHS09 |
Signal Word | Warning | |
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Acetylcholine protects mesenteric arteries against hypoxia/reoxygenation injury via inhibiting calcium-sensing receptor.
J. Pharmacol. Sci. 127 , 481-8, (2015) The Ca(2+)-sensing receptor (CaSR) plays an important role in regulating vascular tone. In the present study, we investigated the positive effects of the vagal neurotransmitter acetylcholine by suppressing CaSR activation in mesenteric arteries exposed to hyp... |
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Parathyroid-specific deletion of dicer-dependent microRNAs abrogates the response of the parathyroid to acute and chronic hypocalcemia and uremia.
FASEB J. 29 , 3964-76, (2015) MicroRNAs (miRNAs) down-regulate gene expression and have vital roles in biology but their functions in the parathyroid are unexplored. To study this, we generated parathyroid-specific Dicer1 knockout (PT-Dicer(-/-) ) mice where parathyroid miRNA maturation i... |
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